Kinetics ofin VivoGlycogen Synthesis in the Estrogen-Stimulated Rat Uterus

Structural changes in the luminal epithelium of the porcine uterus between days 10 and 19 of the estrous cycle

“…Injection of rats with estrogen stimulates elevated rates of glucose transport into the uterine epithelial cells (Szego and Roberts, 1953;Bitman et al, 1965;Roskoski and Steiner, 19671, which precedes previously reported estrogen-induced accumulation of glycogen (Boettinger, 1946;Wallas, 1952) as well as an increased rate of efflux from the uterus (Roskoski and Steiner, 1967). The presence of a glucose transport protein in plasma-membrane vesicles has been identified in the rat (Meier and Garner, 1985) and i s stimulated by estradiol.…”

Glycogen and Water Responses to Estrogen in the Hamster Reproductive Tract

“…In the rat, 1 jug of estradiol yields a maximal response, a 3-fold increase in glycogen synthesis, which is complete within a 10 hr interval (3). The glycogen increase is mostly in the uterine myometrial portion and can be induced with estrone, estradiol, diethylstilbestrol in the immature animal (2).…”

Glycogen Metabolism of Normal Human Myometrium and Leiomyoma – Possible Hormonal Control

“…Several papers on the effect of sex hormones, especially of estrogens, on glycogen metabolism of rat uterus have been published, but in most studies no clear distinction between endometrium and myome trium was attempted [2][3][4], In the present study glycogen metabolism in myometrium of women in the last trimester of pregnancy was compared to that of nonpregnant women aged 42-50 years and of postmenopausal women. In several patients with myomas glycogen content and activities of enzymes of gly cogen metabolism of the myoma were found to differ from that of the surrounding muscle and to resemble the pattern found in uterine muscle of pregnant women.…”