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Physiological Metrology

“…Thus, we may draw the following conclusions: (1) skin transplants are more successful if the donor and the recipient have similar CCBMSs; (2) the greater the difference in CCBMS, the stronger the rejection of the skin transplant and the inflammatory cellular infiltration; and (3) the longer the infiltration lasts, the slower the recipient's own tissues regenerate [13].…”

“…This concept has been tested experimentally, and the possibility to use, for these purposes, the integrated parameter of metabolic similarity (the so-called conventional criterion of body metabolic status; CCBMS) proposed earlier has been estimated [1,2,13].…”

“…Additional equality criterion has been developed on the basis of pharmacological metrological approaches. In this case, the metabolic equality between the donor and the recipient is regarded as a factor of histocompatibility [13].…”

“…Neither "fast" nor "slow" NAT2 phenotype exhibited any advantage. The frequencies of fast and slow NAT2-acetylators in different ethnic groups vary in a wide range [7,8].Twenty-eight polymorphic variants of the NAT2 gene have been found [13]. It has been demonstrated that the distribution of NAT2 phenotypes is associated with geographic latitude [15].…”