Klinische und experimentelle Untersuchungen zur Physiologie der Tuba Eustachii

Sudhoff, Holger; Ockermann, Thorsten; Mikolajczyk, Rafael; Ebmeyer, Jörg; Korbmacher, D.; Garten, Désirée; Schreiber, S.

doi:10.1007/s00106-009-1908-1

Cited by 27 publications

(6 citation statements)

References 18 publications

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“…Gerbil [15], chinchilla [16] and rabbit [17] have been used to investigate certain aspects of an ET treatment. These models are appropriate for biocompatibility tests [17], but even if the overall structure and histology of the tube is comparable to human [18], the size of the ET is much smaller.…”

Section: Introductionmentioning

confidence: 99%

Treatment of Middle Ear Ventilation Disorders: Sheep as Animal Model for Stenting the Human Eustachian Tube – A Cadaver Study

et al. 2014

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Eustachian tube disorders can lead to chronic otitis media with consecutive conductive hearing loss. To improve treatment and to develop new types of implants such as stents, an adequate experimental animal model is required. As the middle ear of sheep is known to be comparable to the human middle ear, the dimensions of the Eustachian tube in two strains of sheep were investigated. The Eustachian tube and middle ear of half heads of heathland and blackface sheep were filled with silicone rubber, blended with barium sulfate to induce X-ray visibility. Images were taken by digital volume tomography. The tubes were segmented, and a three-dimensional model of every Eustachian tube was generated. The lengths, diameters and shapes were determined. Additionally, the feasibility of endoscopic stent implantation and fixation was tested in cadaver experiments. The length of the tube between ostium pharyngeum and the isthmus and the diameters were comparable to published values for the human tube. The tube was easily accessible through the nose, and then stents could be implanted and fixed at the isthmus. The sheep appears to be a promising model for testing new stent treatments for middle ear ventilation disorders.

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Section: Introductionmentioning

confidence: 99%

Treatment of Middle Ear Ventilation Disorders: Sheep as Animal Model for Stenting the Human Eustachian Tube – A Cadaver Study

et al. 2014

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“…A dysfunction of the Eustachian tube, especially an obstruction, results in faulty pressure conditions in the middle ear and pneumatised mastoid process. In addition to complaints, such as an unpleasant sensation of pressure or fullness in the affected ear, tube ventilation dysfunction is often accompanied by chronic middle ear infections, with or without cholesteatoma [1,3,4,5,6,7]. …”

Section: Introductionmentioning

confidence: 99%

Balloon Dilatation of the Eustachian Tube: Postoperative Validation of Patient Satisfaction

Bast

Frank

Schrom

2013

ORL

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Objectives: The Eustachian tube is responsible for ventilation, protection and drainage of the middle ear. Dysfunction of the Eustachian tube can lead to impairments ranging from inadequate pressure equalisation in the middle ear and pneumatised mastoid process to cholesteatoma. Conventional surgical interventions for chronic tube dysfunction have not brought resounding clinical success. However, the ‘Bielefelder Balloon dilatation' constitutes a new and, judging from early results, very effective treatment for chronic tube dysfunction. Proof of the efficacy of the surgical procedures is provided by objective clinical factors, but for quality assurance, the assessment of the subjective quality of life of patients must also be taken into account. To measure health-related quality of life, standardised questionnaires are used which have been tested for reliability, validity and sensitivity. Methods: A total of 30 patients were included in the study. The patient survey was conducted retrospectively, and validation of patient satisfaction was carried out with the Glasgow Benefit Inventory (GBI). Results: GBI analysis revealed significant improvements in the total score as well as in general and physical health. Conclusions: The Bielefelder Balloon dilatation is a new and safe treatment for chronic tube dysfunction, which had a significant positive influence on the postoperative quality of life of our patient cohort.

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“…[8][9][10] In our experience, when following up children with long-term tubes, these tests, supported by adequate surgical and/or non-surgical therapy, are critical in order to tailor the correct timing of the intubation period. It is an intriguing idea to follow patients for two years, perform tubomanometry and then undertake elective removal of the T-tube followed by approximation and freshening of the tympanic membrane edges.…”

Section: -10mentioning

confidence: 99%

“…7 When assessing the appropriate intubation period during the follow up of the paediatric patient, we have observed the usefulness of both nasal endoscopy and tubomanometry at low pressures. [8][9][10] Nasal endoscopy allows evaluation of the conformation of the tubaric ostium and the motility of the peristaphyline muscles, thus excluding any mechanical tubal obstruction, for example due to peritubaric recurrence of adenoid hypertrophy, oedema, hyperaemia related to laryngopharyngeal reflux, or chronic exudative inflammation.…”

mentioning

confidence: 99%

Long-term ventilation tubes: for how long should they be used?

Rinaldi

Messaoudi²,

Gaini

et al. 2013

J. Laryngol. Otol.

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Klinische und experimentelle Untersuchungen zur Physiologie der Tuba Eustachii

Abstract: Both our animal model and the clinical application of tube manometry are likely to be useful for further experimental and clinical studies.

Cited by 27 publications

References 18 publications

Treatment of Middle Ear Ventilation Disorders: Sheep as Animal Model for Stenting the Human Eustachian Tube – A Cadaver Study

Treatment of Middle Ear Ventilation Disorders: Sheep as Animal Model for Stenting the Human Eustachian Tube – A Cadaver Study

Balloon Dilatation of the Eustachian Tube: Postoperative Validation of Patient Satisfaction

Long-term ventilation tubes: for how long should they be used?

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