Klinische Wirksamkeiten der Magnetfeldtherapie - eine Literaturubersicht

Abstract

To verify the efficacy of electromagnetic fields on various diseases we conducted a computer-assisted search of the pertinent literature. The search was performed with the aid of the Medline and Embase database (1966-1998) and reference lists. Clinical trials with at least one control group were selected. The selection criteria were met by 31 clinical studies. 20 trials were designed double-blind, randomised and placebo-controlled. The studies were categorised by indications. Electromagnetic fields were applied to promote bone-healing, to treat osteoarthritis and inflammatory diseases of the musculoskeletal system, to alleviate pain, to enhance healing of ulcers and to reduce spasticity. The action on bone healing and pain alleviation of electromagnetic fields was confirmed in most of the trials. In the treatment of other disorders the results are contradictory. Application times varied between 15 minutes and 24 hours per day for three weeks up to eighteen months. There seems to be a relationship between longer daily application time and positive effects particular in bone-healing. Patients were treated with electromagnetic fields of 2 to 100 G (0.2 mT to 10 mT) with a frequency between 12 and 100 Hz. Optimal dosimetry for therapy with electromagnetic fields is yet not established.

Weak Power Frequency Magnetic Field Acting Similarly to EGF Stimulation, Induces Acute Activations of the EGFR Sensitive Actin Cytoskeleton Motility in Human Amniotic Cells

“…It is also clear that cells undergoing tumorigenesis have been observed to have altered cytoskeletons with enhanced motility and less polarity [30]–[31]. Similar effects were also observed in migrating cells during many biological processes, such as tissue repair and regeneration [1], [2], [18], [19]. All of these cytoskeletal dynamics of migrating cells are highly associated with the EGFR signal pathway because there is intensive cross talk between the cytoskeleton and the EGFR signal pathways.…”

“…EMFs have been applied in medical therapies and were reported to be able to improve wound healing and tissue repair [18]–[19] and to accelerate the proliferation of osteoblasts to promote fracture healing [19]–[20].…”

Results from Conservative Treatments for Intervertebral Disc Protrusion in Sportsmen

“…The invigoration of the trunk musculature obtained by individual physiotherapy and muscle stamina training leads to smaller loads on the intervertebral disc due to improved muscular control of the spinal column. Good results were obtained by adapted lying positions (90 ° angles at both hip-and knee-joints), extensiontherapy, Tilscher infusion therapy, as well as local warmth median 10 20 8 20 10 22 interquartile range 1 7 4 9 4 3 confi dence interval 9 -10 18 -25 7 -11 12 -21 7 -11 21 -24 applications, magnetic fi eld therapy, acupuncture or electrotherapy [9,16] . It must be said clearly, however, that the biological working mechanisms behind the therapy of lumbar spine complaints are not fully understood at present.…”

Adjuvante Behandlung der Gonarthrose mit schwachen pulsierenden Magnetfeldern

“…Dennoch zeigen die generell positiven Effekte, vor allem im Schmerz-wie im Funktionsbereich -nicht zuletzt auch im Hinblick auf die geringen Nebenwirkungsrisiken -einen praktischen Vorteil auf, der unter Kosten-Nutzen-Aspekten umso größer sein könnte, je länger die Therapie eingesetzt würde. Denn die laufenden Kosten der Therapie sind gering, mehrere Studien verweisen auf eine Effektsteigerung nach längerer Anwendungsdauer [3,5,7,14,16]. Der relativ rasche Rückgang der positiven Effekte innerhalb von 4 -6 Wochen nach Therapieende lässt eine längere Therapiedauer empfehlenswert erscheinen.…”