Knee osteoarthritis treated with acupuncture based on syndrome differentiation: a randomized controlled trial

Fu, M Y

doi:10.1016/s1003-5257(12)60035-x

Cited by 4 publications

(9 citation statements)

References 4 publications

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“…These 19 studies were published between 1992 and 2014. [43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61] The number of participants in the studies varied from 20 to 712. Two studies were conducted in the USA, [43][44][45] three in Germany, 46 58 59 four in China, 47-49 61 three in the UK, 52 56 57 and one each in Australia, 50 Japan, 51 Greece, 53 Iran, 54 Thailand 55 and Denmark.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Two studies were conducted in the USA, [43][44][45] three in Germany, 46 58 59 four in China, 47-49 61 three in the UK, 52 56 57 and one each in Australia, 50 Japan, 51 Greece, 53 Iran, 54 Thailand 55 and Denmark. 60 Thirteen studies compared acupuncture as a primary treatment against different types of control intervention, 43-45 47 48 50-52 56-60 of which two consisted of no treatment, 50 56 three used allocation to a waiting list, [58][59][60] two used pharmaceutical interventions (namely sodium hyaluronate 47 and glucosamine hydrochloride capsules 48 ), and one each used standard care (oral therapy), 43 usual care (medications and interventions), 52 education, 44 45 topical poultices, 51 isometric exercises 54 and home exercises. 57 Three studies tested electroacupuncture (EA) alone compared with ibuprofen, 49 etoricoxib 55 and transcutaneous electrical nerve stimulation.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…56 Regarding other potential sources of bias (including lack of intention-to-treat analysis, information about cointerventions, compliance, acceptability and baseline comparisons), 16 studies were found to demonstrate an unclear risk of bias due to the lack of intention-to-treat analysis, insufficient information about cointerventions, compliance and acceptability. [45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61] Additionally, one of these trials failed to report baseline WOMAC and VAS information. 56 The completeness of the STRICTA checklist for each study is detailed in table 2.…”

Section: Study Qualitymentioning

confidence: 99%

“…43-53 55-58 All studies reported the treatment regimen very well. [43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61] Only two trials applied cointerventions. 52 53 As for practitioner background, five studies reported the duration of relevant training 46 51 52 58 59 ; six studies the length of clinical experience 44-46 50-52 ; and only one study reported the therapists' expertise in the specific condition.…”

Section: Study Qualitymentioning

confidence: 99%

“…48 Four studies reported adverse events associated with acupuncture treatment of chronic knee pain. One study examining the use of acupuncture as adjunctive therapy reported that seven minor adverse events occured in the acupuncture group.…”

Section: Acupuncture Versus Glucosamine Hydrochloride Capsulesmentioning

confidence: 99%

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Updated Systematic Review and Meta-Analysis of Acupuncture for Chronic Knee Pain

et al. 2017

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Objective To assess the effectiveness and safety of acupuncture for the treatment of chronic knee pain (CKP). Methods We searched the MEDLINE, EMBASE, Cochrane CENTERAL, CINAHL and four Chinese medical databases from their inception to June 2017. We included randomised controlled trials of acupuncture as the sole treatment or as an adjunctive treatment for CKP. The primary outcome was pain intensity measured by visual analogue scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale and 11-point numeric rating scale. Secondary outcome measurements included the 36-Item Short Form Health Survey and adverse events. The quality of all included studies was evaluated using the Cochrane risk-of-bias criteria and the STRICTA (Standards for Reporting Interventions in Controlled Trials of Acupuncture) checklist. Results Nineteen trials were included in this systematic review. Of these, data from 17 studies were available for analysis. Regarding the effectiveness of acupuncture alone or combined with other treatment, the results of the metaanalysis showed that acupuncture was associated with significantly reduced CKP at 12 weeks on WOMAC pain subscale (mean difference (MD) −1.12, 95% confidence interval (CI) −1.98 to −0.26, I

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Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Qualitymentioning

confidence: 99%

Section: Study Qualitymentioning

confidence: 99%

Section: Acupuncture Versus Glucosamine Hydrochloride Capsulesmentioning

confidence: 99%

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Updated Systematic Review and Meta-Analysis of Acupuncture for Chronic Knee Pain

et al. 2017

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Effect of 4 weeks vs 8 weeks of acupuncture for knee osteoarthritis in China: protocol for a randomised controlled trial

Yu,

Liu,

Wang

et al. 2024

BMJ Open

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IntroductionKnee osteoarthritis represents the prevalent and incapacitating disease. Acupuncture, a widely used clinical treatment for knee osteoarthritis, has been shown to ameliorate pain and enhance joint function in affected individuals. However, there is a lack of evidence comparing different courses of acupuncture for knee osteoarthritis. In this trial, we will assess the effect of 4 weeks vs 8 weeks of acupuncture in patients with knee osteoarthritis.Methods and analysisThe protocol is a pragmatic, parallel, two-arm randomised controlled trial, with the data analyst and assessor being blinded. 148 eligible patients with knee osteoarthritis will be randomly allocated in a 1:1 ratio to receive 4-week or 8-week acupuncture. Electroacupuncture will be administered three times per week for 4 or 8 weeks, respectively. Patients with knee osteoarthritis in both groups will be followed up to 26 weeks. The primary outcome is the response rate at week 26, and secondary outcomes include knee joint pain, knee joint function, knee joint stiffness, quality of life, patient global assessment, the Osteoarthritis Research Society International response rate and rescue medicine. A cost-effectiveness analysis will be carried out over 26 weeks.Ethics and disseminationThe protocol has been approved by the Medical Ethical Committee of Beijing University of Chinese Medicine (2023BZYL0506). The study findings will be disseminated through presentation in a medical journal. Additionally, we plan to present them at selected conferences and scientific meetings.Trial registration numberChinese Clinical Trials Registry (ChiCTR2300073383;https://www.chictr.org.cn/showproj.html?proj=199310).

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Evaluating Meridian-Sinew Release Therapy for the Treatment of Knee Osteoarthritis

Song

Chen

Sun

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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Objective. In recent years, public health experts have concluded that the impact of osteoarthritis is equal in magnitude to that of cardiovascular disease. Osteoarthritis of the knee is prevalent in the elderly population; however, there are currently no effective treatments for this condition. In this study, we investigated the efficacy of “meridian-sinew release,” a newly developed technique which entails using a meridian-sinew scope and a meridian-sinew knife to treat osteoarthritis of the knee. Methods. Patients (N = 90) with knee osteoarthritis were prospectively randomized to meridian-sinew release therapy, acupuncture therapy, or drug therapy groups, respectively. Outcome evaluation included pain, stiffness, physiological function, total symptom score, and overall changes in the condition. Results. After 12 weeks, patients' general assessment (GA) and doctors' general assessment (GA) of the condition were not significantly different among the three groups. However, significant differences in primary endpoint pain, joint stiffness, and total symptom score were found between the meridian-sinew group and the acupuncture group and between the meridian-sinew group and the control group (P < 0.05). No adverse events occurred during the trial. Conclusion. Our study suggests that meridian-sinew release therapy can improve knee osteoarthritis, alleviate joint pain, and improve functional movement disorder. It is a safe and effective treatment for knee osteoarthritis.

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Knee osteoarthritis treated with acupuncture based on syndrome differentiation: a randomized controlled trial

Cited by 4 publications

References 4 publications

Updated Systematic Review and Meta-Analysis of Acupuncture for Chronic Knee Pain

Updated Systematic Review and Meta-Analysis of Acupuncture for Chronic Knee Pain

Effect of 4 weeks vs 8 weeks of acupuncture for knee osteoarthritis in China: protocol for a randomised controlled trial

Evaluating Meridian-Sinew Release Therapy for the Treatment of Knee Osteoarthritis

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