Knewton (An adaptive learning platform available at https://www.knewton.com/)Knewton (An adaptive learning platform available at https://www.knewton.com/)

Conklin, Thomas A.

doi:10.5465/amle.2016.0206

Cited by 215 publications

(271 citation statements)

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“…The thesis that the development of a personalized learning environment should be aimed not only at student performance in academic parameters but also at creating a transformative environment conducive to personal development coincides with the conclusions of this study [36,37]. The authors support the opinion that there is a need to explore how educators use data, how technologies are created to support learners, and how the content and curriculum are developed to support individual learning [14].…”

Section: Comparative Perspectivesupporting

confidence: 70%

Personalized Computer Support of Performance Rates and Education Process in High School: Case Study of Engineering Students

et al. 2021

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To date, the existing principles of a unified approach to schooling do not meet the requirements of a fundamental socio-economic transition characterized by personalization and customization of products and services that concern all areas, including education. The paradigm of education systems is being restructured in many countries towards a new approach of personalized learning that is adapted to students' needs, allows them to choose individual educational trajectories, and respects unique skills and qualities. The study aimed to determine the impact of personalization on the academic performance of engineering students in physics. The experiment on personalized student support was conducted during the academic year 2018-2019 at I.T. Trubilin Kuban State Agrarian University. The sample covered 78 students. The starting point of the research was the assessment of students' skills in mathematics, as the study of physics is based on mathematical analysis and interpretation. Test in physics and the criterion of alpha Kronbach (test reliability is determined with a coefficient of 0.87) were used as a toolkit for research. Besides, the statistical tools and covariance analysis of data processing were employed. The research was supported by the SPSS Statistics software package. According to the results obtained, higher post-test scores were recorded for students in the experimental group. The personalized learning has been found to have a significant impact on the academic performance of students. Those with low and medium ability in mathematics demonstrated higher growth in academic achievement than students with recorded high aptitude scores. A correlation between learning methods and mathematical skills to achieve high academic performance has been established. The influence of personalization in the learning process was determined to be moderately high (determinacy coefficient of 72.6%). The study is relevant for the development of constructive approaches that could help teachers improve their approach to learning and students improve academic achievements. The results may be of interest to researchers of educational technology, educators, and university administration management.

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Section: Comparative Perspectivesupporting

confidence: 70%

Personalized Computer Support of Performance Rates and Education Process in High School: Case Study of Engineering Students

et al. 2021

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“…In June 2006, natalizumab was reintroduced to the market and reapproved by the FDA as a monotherapy for highly active MS, but with a black box warning describing an increased risk for PML with its use and required adherence to a special program developed by the FDA known as Tysabri Outreach Unified Commitment to Health, which is only available in the United States (43). This is a restricted distribution program aimed at minimizing the risks associated with the use of natalizumab.…”

Section: Natalizumab Reintroduction With a Risk-management Programmentioning

confidence: 99%

“…Only prescribers and patients enrolled in the Tysabri Outreach Unified Commitment to Health program may prescribe and receive natalizumab. Also, the dispensing and infusion of natalizumab can only be done through certain pharmacies and infusion centers that are authorized by the program (43).…”

Section: Natalizumab Reintroduction With a Risk-management Programmentioning

confidence: 99%

Natalizumab for Multiple Sclerosis: A Case in Point for the Impact of Translational Neuroimmunology

Shirani

Stüve

2017

The Journal of Immunology

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Advances in translational neuroimmunology over the last two decades have revolutionized the treatment of relapsing forms of multiple sclerosis. A pathological hallmark of multiple sclerosis is the presence of leukocytes in the areas of disease activity in the CNS. Natalizumab inhibits the trafficking of lymphocytes from the blood into the brain and spinal cord by blocking the adhesion molecule α-integrin. Representing the enormous success of a molecular targeted approach, natalizumab was the first mAb approved for the treatment of relapsing-remitting multiple sclerosis. However, only a few months after its approval, natalizumab was withdrawn from the market because of an unanticipated life threatening adverse effect: progressive multifocal leukoencephalopathy. Natalizumab was later reintroduced with required adherence to a strict monitoring program. In this article, we review the bench-to-bedside journey of natalizumab, along with the lessons learned from postmarketing studies.

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“…For the design of plants, the GPS-X software developed by Hydromantis Inc. was used. GPS-X (Hydromantis Inc. 2021) is the leading and the most advanced software for design, modeling and optimization of wastewater treatment plants. Generally, the process of designing greywater treatment systems consisted of constructing a layout of each respective greywater treatment plant, identification of the most significant and sensitive design parameters by optimization of these parameters to achieve satisfactory effluent quality at a minimum cost and space.…”

Section: Membrane Bioreactormentioning

confidence: 99%

Design and modeling of an on-site greywater treatment system for a hotel building

Kobeyev

Tokbolat

Nazipov

et al. 2022

IJBPA

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PurposeAs the United States is making a significant move toward rejoining the Paris Agreement on climate change, there is a high demand for sustainable solutions across various industries, including construction and hospitality sectors. The aim of this project was to design and model an on-site greywater treatment system for a hotel building for the effective reuse of sewage water. The study considered Los Angeles, California, as a case study location and referred to respective climate conditions and construction standards.Design/methodology/approachThis study considered various options of greywater treatment plants such as membrane bioreactor (MBR), sequencing batch reactor and reverse osmosis with upflow anaerobic sludge blanket which were carefully reviewed and modeled using the GPS-X software. The design and modeling results were verified by hand calculations and were followed by the estimation of capital and operational expenses required for the implementation of the plants.FindingsHaving relatively low capital and operational expenditure requirements as well as superior technical performance, the MBR plant proved to be the most effective solution for the considered location and standards and was recommended for use in hotel buildings.Practical implicationsDesigning and modeling several greywater treatment plants allowed selecting the most optimal option which in the long run will help to preserve the eco-system, stay compliant with the government laws and regulations and be financially sustainable.Originality/valueThe outcomes of the present study provide a detailed procedure for designing and modeling a greywater treatment plant for a hotel building that can be used for the localities with a similar climate. The most effective option selected as a result of cost-benefit analysis provides an efficient and viable solution for the relevant industry and the type of buildings.

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Knewton (An adaptive learning platform available at https://www.knewton.com/)Knewton (An adaptive learning platform available at https://www.knewton.com/)

Cited by 215 publications

References 0 publications

Personalized Computer Support of Performance Rates and Education Process in High School: Case Study of Engineering Students

Personalized Computer Support of Performance Rates and Education Process in High School: Case Study of Engineering Students

Natalizumab for Multiple Sclerosis: A Case in Point for the Impact of Translational Neuroimmunology

Design and modeling of an on-site greywater treatment system for a hotel building

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