IntroductionPregnancy is a determining period for both mother and fetus. No mother would jeopardize her baby's health at any cost. Nowadays, most women dye their hair at some points in their lives, sometimes as early as 18 years old (1-3). It is not clear whether hair color would affect the fetus or not. Studies have shown a possible association between hair coloring during pregnancy, and low birth weight (LBW), neuroblastoma, and leukemia in the offspring (4-7). There is a report on increased neonatal abnormalities in mothers who used chlorinated solvents and glycol ether for hair dyeing during pregnancy. Still, the report was criticized because of the lack of biological plausibility (8). Blackmore-Prince et al failed to show the association of dyeing hair three months before pregnancy and during pregnancy with preterm labor or LBW in black women (9). Different studies raised concerns about the association of the effect of glycol ethers and oxygenated solvents which are used in cosmetic products with neurocognitive abnormalities and potential developmental effects on the male genital system (10,11), and thus far, studies have failed to prove the adverse association (12).Despite limited evidence on the adverse effects of hair coloring during pregnancy, with a justification of "minimal systemic absorption on healthy skin", hair dyes are considered to be safe during pregnancy (13,14). However, there is no convincing evidence aimed to examine the relationships between hair coloring during pregnancy and other unwanted outcomes. According to our clinical experience, most Iranian women believe that hair coloring during pregnancy would affect the child; however, if they want to dye their hair, they do it at the end of the third trimester. Considering these, the main goal of this study was to examine the association between hair coloring and intrapartum and neonatal outcomes such as preterm labor and Apgar scores.
Materials and MethodsThis was an explorative cross-sectional study; therefore, we did not use a formal sample size calculation and evaluated all participants' data. The study was carried out in Talegani teaching hospital of Tabriz University of Abstract Objectives: Using hair dye has spread globally in recent years. Concerns have arisen about the safety of hair dyes during pregnancy. The primary goal of this study was to examine the association between hair coloring and pregnancy outcomes. Materials and Methods: This cross-sectional study was conducted on 2040 pregnant women aged 14 to 48 years, in Talegani teaching hospital of Tabriz University of Medical Sciences from January 2017 to December 2019. Three trained midwives collected relevant information from the women on the admission to the labor room and recorded pregnancy outcomes. Chi-square test of independence with post hoc tests and logistic regression analysis were used for data analysis. Odds ratios with a 95% confidence interval and contributing effect sizes were reported. The significance level was set at P ≤ 0.05. Results: The majority of participan...