Knowledge, attitudes, and practices regarding exclusive breastfeeding among HIV‐positive mothers in Uganda: A qualitative study

Operto, Emily

doi:10.1002/hpm.2966

Cited by 18 publications

(13 citation statements)

References 28 publications

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“…The lack of an early maternal diagnosis leads to a child’s late diagnosis. In our population, infected children were born mostly through vaginal delivery, were breastfed, and had a higher age of diagnosis, corroborating with reports in the literature [ 36 , 37 , 38 , 39 , 40 ]. During vaginal delivery, infants are exposed to HIV-1 via fluids from the birth canal that penetrate their oropharyngeal cavity [ 36 ].…”

Section: Discussionsupporting

confidence: 91%

Clinical–Epidemiological Characteristics and IFITM-3 (rs12252) Variant Involvement in HIV-1 Mother-to-Children Transmission Susceptibility in a Brazilian Population

Leandro

Silva

Rodrigues

et al. 2023

Life

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Mother-to-children transmission (MTCT) is the main infection route for HIV-1 in children, and may occur during pregnancy, delivery, and/or postpartum. It is a multifactorial phenomenon, where genetic variants play an important role. This study aims at analyzing the influence of clinical epidemiological characteristics and a variant (rs12252) in interferon-induced transmembrane protein 3 (IFITM-3), a gene encoding an important viral restriction factor, on the susceptibility to HIV-1 mother-to-children transmission (MTCT). A case–control study was performed on 209 HIV-1-infected mothers and their exposed infected (87) and uninfected (122) children from Pernambuco, Brazil. Clinical–epidemiological characteristics are significantly associated with MTCT susceptibility. Transmitter mothers have a significantly lower age at delivery, late diagnosis, deficiency in ART use (pregnancy and delivery), and detectable viral load in the third trimester of pregnancy compared with non-transmitter mothers. Infected children show late diagnosis, vaginal delivery frequency, and tend to breastfeed, differing significantly from uninfected children. The IFITM-3 rs12252-C allele and TC/CC genotypes (dominant model) are significantly more frequent among infected than uninfected children, but the statistical significance does not remain when adjusted for clinical factors. No significant differences are observed between transmitter and non-transmitter mothers in relation to the IFITM-3 variant.

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Section: Discussionsupporting

confidence: 91%

Clinical–Epidemiological Characteristics and IFITM-3 (rs12252) Variant Involvement in HIV-1 Mother-to-Children Transmission Susceptibility in a Brazilian Population

Leandro

Silva

Rodrigues

et al. 2023

Life

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“…Most (70.4%; n=38) of respondents agreed that they had a fear of breastfeeding exclusively due to stigma. Similarly, the results tallied with that of the study in Ethiopia where (63.4%; n= 34) of participants desisted from EBF due to fear of stigma 24 . Furthermore, 70.4%(n=38) of participants in this study indicated that they had a fear of breastfeeding exclusively due to the belief that breastfeeding may cause a change in their body shapes, but agreed that breast milk alone can satisfy the baby for up to six months.…”

Section: Discussionsupporting

confidence: 73%

Knowledge, attitudes and practices of HIV-positive mothers regarding the benefits of exclusive breastfeeding at a regional hospital in the north east of Namibia

Ashipala¹,

Shikukumwa²,

Joel³

2021

Afr H. Sci.

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Background: In sub-Saharan Africa, over 1,000 newborns are infected with HIV every day, despite available medical in- terventions. Mother-to-child transmission (MTCT) remains one of the primary sources of HIV infection in children and without interventions 40% of babies born from HIV-positive mothers would be infected with the virus. It is estimated that 300 000 children become infected with HIV worldwide, whilst 1.5 million children die when their mothers opt for other choices instead of breastfeeding. Objective: The purpose of the study was to assess and describe the knowledge, attitudes and practices of HIV-positive mothers regarding the benefits of exclusive breastfeeding at Rundu Intermediate Hospital, Kavango East Region in Namibia. Method: The study was a descriptive cross-sectional survey that used convenience sampling, as the researcher sought to use subjects available during the time of study to select 79 HIV positive mothers. Results: Participants in this study (94%; n=51) had good knowledge of the benefit of exclusive breastfeeding and that the benefits of breastfeeding outweigh the risk of HIV transmission from mother to child. The results confirmed that (77.2%; n=42) of the mothers opted to take ART with the babies until they stop breastfeeding. Conclusion: HIV positive mothers had good knowledge, attitudes and practices regarding the benefits of exclusive breast- feeding. A significant number of mothers were, however, not sure about breastfeeding exclusively for 6 months as they would stop if offered free formula milk for the baby. Support by the fathers and others in the community is vital. Keywords: Knowledge; HIV; breastfeeding; attitudes; practices; HIV-positive mothers; Namibia.

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“…Women lacking in means are unable to make antenatal consultations with no knowledge of serological status. Numerous studies have also highlighted the role of breastfeeding in the mother-to-child transmission of HIV1 [27,28] and that of the role of neonatal and child prophylaxis [29]. Regarding the method of breastfeeding, social factors such as knowledge of the serological status by the husband or the in-laws play an enormous role in the choice of the method of breastfeeding despite medical advice, especially in rural areas [30].…”

Section: Discussionmentioning

confidence: 99%

Mother-child HIV-1 transmission in the departments of Mono and Couffo in Benin: incidence and associated factors in 2019

Koudokpon

Dougnon

Kissira

et al. 2020

Preprint

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Background: Despite worldwide success of introducing HIV testing and treatment with antiretroviral drugs, HIV remains a real public health problem. Vertical mother-child transmission is a form responsible for many cases of new infections. This study was therefore carried out in order to reduce the prevalence of mother-to-child transmission of HIV-1 in the departments of Mono and Couffo. Method: For this purpose, a total of 374 dry blood spots (DBS) were collected from infants born to HIV-positive mothers during the year 2019, and these DBS were used for the molecular diagnosis of HIV1 in these infants. Information on the type of treatment, the type of diet of infants was also collected. The viral loads of the mothers before delivery were determined after the last antenatal visits. To do so, a venous blood sample was taken from an EDTA tube. These different samples were used for DNA extraction. The early diagnosis of these infants as well as the determination of the viral load were carried out by RT-PCR using the Roche automated system. The results were analyzed with the chi-square test on the SPSS software. Result: The results showed that 51% of the newborns included in the study were male and the vast majority of the newborns were in the 0-6 month age group. 93.41% of the newborns included in this study were tested negative for early detection by RT-PCR. Significant links were observed between the early diagnosis of newborns and the mother's mode of feeding, the PMTCT protocol, and the viral load of the mothers. Monoprophylaxis was predominant in the newborn PMTCT protocol (96.28%). Conclusion: The national program for the prevention of vertical transmission of HIV from mother to child deserves to be continued and strengthened with the objective of zero newborns infected at birth in the departments of Mono and Couffo.

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Knowledge, attitudes, and practices regarding exclusive breastfeeding among HIV‐positive mothers in Uganda: A qualitative study

Cited by 18 publications

References 28 publications

Clinical–Epidemiological Characteristics and IFITM-3 (rs12252) Variant Involvement in HIV-1 Mother-to-Children Transmission Susceptibility in a Brazilian Population

Clinical–Epidemiological Characteristics and IFITM-3 (rs12252) Variant Involvement in HIV-1 Mother-to-Children Transmission Susceptibility in a Brazilian Population

Knowledge, attitudes and practices of HIV-positive mothers regarding the benefits of exclusive breastfeeding at a regional hospital in the north east of Namibia

Mother-child HIV-1 transmission in the departments of Mono and Couffo in Benin: incidence and associated factors in 2019

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