Kongenitale wortblindheit oder spezifische dyslexie (Congenital word-blindness)

Zerbin-Rüdin, E.

doi:10.1007/bf02653585

Cited by 53 publications

(11 citation statements)

References 19 publications

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“…The concordance rate for DD is then compared between the two sets of twins. A higher concordance rate in the MZ twins would be suggestive of a genetic aetiology for DD, and fittingly this has been shown consistently; 1.00 versus 0.52 [212], 0.91 versus 0.45 [4] and 0.68 versus 0.38 [41]. Twin studies also enable estimates of the heritability of DD, that is the proportion of phenotypic variation attributable to genetic variation, with figures ranging from 0.30 to 0.70 [27,42,64,182], depending on the diagnostic criteria, age and sample size (see Fig.…”

Section: Heritability Of Ddmentioning

confidence: 59%

Genetics of developmental dyslexia

Scerri

Schulte‐Körne

2009

Eur Child Adolesc Psychiatry

191

137

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Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in school-aged children. Linkage studies have identified numerous loci throughout the genome that are likely to harbour candidate dyslexia susceptibility genes. Association studies and the refinement of chromosomal translocation break points in individuals with dyslexia have resulted in the discovery of candidate genes at some of these loci. A key function of many of these genes is their involvement in neuronal migration. This complements anatomical abnormalities discovered in dyslexic brains, such as ectopias, that may be the result of irregular neuronal migration.

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Section: Heritability Of Ddmentioning

confidence: 59%

Genetics of developmental dyslexia

Scerri

Schulte‐Körne

2009

Eur Child Adolesc Psychiatry

191

137

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“…considerable confidence can be placed in the results of this single study. The concordance rate for MZ twins (71 %) tested in the Colorado Reading Project is substantially greater than that for DZ twins (49%), thereby confuming the evidence for a genetic aetiology of reading disability previously obtained by Zerbin-RUdin (1967) and Bakwin (1973).…”

Section: University Of Colorado Bouldermentioning

confidence: 81%

Differential Genetic Aetiology of Reading Disability as a Function of Age

Wadsworth

Gillis

DeFries

et al. 1989

The Irish Journal of Psychology

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“…The study by Zerbin-Rudin [1967] included data from six case studies of "congenital word-blindness," a small Danish twin study, and six pairs of twins from Hallgren's (19501 family study. As shown in Table 2, the proband-wise concordance rates for the 17 M Z and 34 D Z twin pairs in this combined sample are 100% and 52%, respectively.…”

Section: Previous Twin Studiesmentioning

confidence: 99%