Millennials were very familiar with the use of smartphones. Excessive use of smartphones could trigger the problem of phubbing behavior that ignores the interlocutor by focusing more on accessing the applications on his smartphone rather than interacting directly with the individual in front of him. The anxiety of being left behind or unable to receive or update information, called Fear of missing out (FoMO) related to phubbing behavior. Low self-control was a factor in problematic smartphone use, including phubbing behavior. This study aimed to see whether there was a relationship between Fear of missing out (FoMO) and self-control in phubbing behavior in the millennial generation. This research used a quantitative survey with accidental sampling techniques. The number of samples in this study was 400 millennial generations in Indonesia. Data collection techniques are carried out online using Google Forms. The results of data collection were analyzed using multiple regression analysis. The result showed that there was a relationship between Fear of missing out (FoMO) and self-control with phubbing behavior (R = 0.584, R 2 = 0.341, F = 102.542, p = 0.000, p <0.05). The partial t-test found that the self-control variable affected phubbing behavior, and the partial t-test found that FoMO also affected phubbing behavior. Self-control contributed more to phubbing behavior than FoMO.