Konversionen von kognitiven Screenings

Scheffels, Jannik Florian; Kräling, Hannah; Kalbe, Elke; Kessler, Josef

doi:10.1007/s00115-018-0583-4

Cited by 10 publications

(19 citation statements)

References 25 publications

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“…This test is mainly based on auditory items and was developed for detection of mild cognitive impairment (MCI) [32]. It has a higher sensitivity than the Mini-Mental-Status test (MMS) for MCI, and the results can be transposed into MMS score values [33,34]. We used the DemTect primarily as a screening tool to determine whether a participant had to be excluded because of dementia.…”

Section: Cognitionmentioning

confidence: 99%

Effects of home reading training on reading and quality of life in AMD—a randomized and controlled study

Kaltenegger

Kuester

Altpeter-Ott

et al. 2019

Graefes Arch Clin Exp Ophthalmol

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Background Age-related macular degeneration (AMD) causes reading impairment, reduced quality of life (QoL), and secondary depression. We have shown that support with magnifying aids improved reading speed (RS), emotional and cognitive status, and QoL. The present study investigates whether additional reading training (RT) (after adapting to appropriate visual aids) can further improve vision rehabilitation. Methods Patients with dry AMD were randomly assigned to 2 groups. The primary RT group (P-RTG, n = 25) trained with sequentially presented text (RSVP), and the control group (CG, n = 12) performed placebo training (crossword puzzles) and later crossed over to RT, so that altogether 37 participants performed reading training. Patients trained at home on a PC for 6 weeks. RS was assessed during reading printed paragraphs of text aloud. Using a scanning laser ophthalmoscope, we examined fixation stability and preferred retinal locus (PRL) for fixating a cross, as well as PRL and eye movements during reading single words. We assessed emotional status by Montgomery-Åsberg Depression Rating Scale (MADRS), cognitive status by dementia detection test (DemTect) and QoL by Impact of Vision Impairment (IVI) profile. Visual acuity and magnification requirement were examined by standard procedures. All variables were measured before and after placebo training, before and after RT, and after 6 weeks without training (follow-up). Results RS improved significantly in the P-RTG during RT, but not in the CG during placebo training. The effect remained stable at follow-up. Fixation performance and eye movement variables did not change. Emotional status (MADRS) improved in P-RTG during RT and showed a significant difference of the change of scores between the 2 groups. Complete IVI scores improved significantly during RT and remained stable. Conclusion The results indicate that patients with AMD, who already use magnifying aids, benefit from additional RT and that it can contribute in preventing depression and improve QoL. Trial registration The study was registered at the German Clinical Trials Register (DRKS00015609).

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Section: Cognitionmentioning

confidence: 99%

Effects of home reading training on reading and quality of life in AMD—a randomized and controlled study

Kaltenegger

Kuester

Altpeter-Ott

et al. 2019

Graefes Arch Clin Exp Ophthalmol

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“…To the best of our knowledge there are no studies comparing the DemTect with MMSE and MoCa in COPD, but there are data in patients without COPD showing comparable sensitivity of DemTect and MoCa in the detection of minor cognitive change [37, 38].…”

Section: Discussionmentioning

confidence: 99%

The association of cognitive functioning as measured by the DemTect with functional and clinical characteristics of COPD: results from the COSYCONET cohort

et al. 2019

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Alterations of cognitive functions have been described in COPD. Our study aimed to disentangle the relationship between the degree of cognitive function and COPD characteristics including quality of life (QoL).Data from 1969 COPD patients of the COSYCONET cohort (GOLD grades 1–4; 1216 male/ 753 female; mean (SD) age 64.9 ± 8.4 years) were analysed using regression and path analysis. The DemTect screening tool was used to measure cognitive function, and the St. George‘s respiratory questionnaire (SGRQ) to assess disease-specific QoL.DemTect scores were < 9 points in 1.6% of patients and < 13 points in 12% when using the original evaluation algorithm distinguishing between < 60 or > =60 years of age. For statistical reasons, we used the average of both algorithms independent of age in all subsequent analyses. The DemTect scores were associated with oxygen content, 6-min-walking distance (6-MWD), C-reactive protein (CRP), modified Medical Research Council dyspnoea scale (mMRC) and the SGRQ impact score. Conversely, the SGRQ impact score was independently associated with 6-MWD, FVC, mMRC and DemTect. These results were combined into a path analysis model to account for direct and indirect effects. The DemTect score had a small, but independent impact on QoL, irrespective of the inclusion of COPD-specific influencing factors or a diagnosis of cognitive impairment.We conclude that in patients with stable COPD lower oxygen content of blood as a measure of peripheral oxygen supply, lower exercise capacity in terms of 6-MWD, and higher CRP levels were associated with reduced cognitive capacity. Furthermore, a reduction in cognitive capacity was associated with reduced disease-specific quality of life. As a potential clinical implication of this work, we suggest to screen especially patients with low oxygen content and low 6-MWD for cognitive impairment.

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“…Since the studies used different tests to evaluate cognitive impairment, the results are not directly comparable. Thus, we transformed the DemTect scores into MoCA scores using suggested conversion tables (23). However, the prevalence rate of cognitive impairment stayed significant lower in our sample (22.3%) compared to the rate reported by Gupta et al (9).…”

Section: Discussionmentioning

confidence: 99%

“…There are calculated bidirectional conversion tables available allowing the conversion and comparison of the German versions of the DemTect and the two other frequently used screening instruments MoCA and Mini-Mental State Examination (MMSE) (10, 22, 23).…”

Section: Methodsmentioning

confidence: 99%

Prevalence and Correlates of Cognitive Impairment in Kidney Transplant Patients Using the DemTect—Results of a KTx360 Substudy

et al. 2019

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Cognitive impairment in kidney transplantation (KTx) patients is associated with allograft survival and mortality. However, the prevalence of cognitive impairment after KTx is still understudied. Thus, we aimed to assess the prevalence of cognitive impairment in KTx patients and to identify sociodemographic, medical, donation-specific, and psychological variables associated with cognitive impairment. In this cross-sectional two-center study, 583 KTx patients participated in a structured post-transplant care program. The DemTect was used to assess cognition, and cognitive impairment was defined as a score of < 13. Mean age was 52.11 years, 59% were male, 27.4% had ≥12 years of school attendance, and 85.9% had hypertension. The prevalence of cognitive impairment was 15.6%. Cognitive impairment was significantly associated with higher age, male sex, lower educational level, subjective perception of cognitive decline, higher rates of hypertension, lower kidney functioning, and obesity (BMI > 30 kg/m2). Using logistic regression analysis, all variables except age remained significant. Our results suggest that cognitive impairment affects a significant number of patients after KTx. Transplant centers may consider screening for cognitive impairment using objective tests, especially in patients with a high-risk profile. Furthermore, studies with longitudinal designs are required in order to assess moderators and mediators for cognitive trajectories.

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Konversionen von kognitiven Screenings

Cited by 10 publications

References 25 publications

Effects of home reading training on reading and quality of life in AMD—a randomized and controlled study

Effects of home reading training on reading and quality of life in AMD—a randomized and controlled study

The association of cognitive functioning as measured by the DemTect with functional and clinical characteristics of COPD: results from the COSYCONET cohort

Prevalence and Correlates of Cognitive Impairment in Kidney Transplant Patients Using the DemTect—Results of a KTx360 Substudy

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