Krukenberg’s tumour unilateral giant metachronous of colonic origin – Case report

Zogbi, Luciano; Isaías, Angélica; Machado, Pedro Augusto; Neutzling, Aluísio; Juliano, Camila Nóbrega

doi:10.1016/j.ijscr.2017.10.029

Cited by 2 publications

(4 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The ovary can host the most diverse and rare types of neoplasms. In addition, it can reach large dimensions until the first symptoms appear [ [7] , [8] , [9] , [10] , [11] ]. This report describes a case of an unusual disease, treated radically with optimal survival and effective cure, which is important to enrich the current literature about rare ovarian neoplasms.…”

Section: Discussionmentioning

confidence: 99%

Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report

Zogbi

Gonçalves

Tejada

et al. 2018

Annals of Medicine and Surgery

Self Cite

View full text Add to dashboard Cite

IntroductionMalignant ovarian germ cell tumors (MOGCTs) are rare malignancies with an incidence of about 0.5/100,000. They account for less than 5% of all ovarian tumors, of which 32.8% are dysgerminomas, the female analogue of seminomas. These tumors occur in all age groups, with peak incidence below the age of 20 years in women.AimTo describe the case of a bilateral ovarian dysgerminoma treatment with 11-year follow-up.MethodsCase report with details regarding clinical history, surgical treatment, chemotherapy and follow up. We include a brief literature review.ResultsThe patient underwent radical surgery for an advanced dysgerminoma, 20 cm in length, that compromised the contralateral ovary and sigmoid. Neoplastic cells were found in ascitic fluid. Subsequently, she underwent adjuvant chemotherapy according to a standard protocol. She has survived disease-free for more than 11 years.ConclusionsDysgerminoma is a malignant neoplasm that, similar to other cancers, is easier to treat when diagnosed early. However, cures may be obtained even in advanced cases.

show abstract

Section: Discussionmentioning

confidence: 99%

Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report

Zogbi

Gonçalves

Tejada

et al. 2018

Annals of Medicine and Surgery

Self Cite

View full text Add to dashboard Cite

show abstract

“…Conversely, ovarian metastases occur in 5-10% of women with metastatic colorectal cancer [12]. Most of the giant ovarian tumors reported were more than 25 cm in diameter [6,9,10,13]. A pretreatment differential diagnosis between primary ovarian cancer and metastatic tumor is more difficult when the ovarian tumor is huge [5], since severe symptoms such as abdominal distention and progressive tumor growth, may hinder further examinations and limit the time for a preoperative assessment.…”

Section: Discussionmentioning

confidence: 99%

“…Presently, a precise diagnosis of ovarian tumor depends on the histopathological findings of excised specimen. An immunohistochemical evaluation is essential for distinguishing between primary and metastatic ovarian carcinoma [6]. Colorectal carcinomas are generally negative for CK7 but positive for CK20 and CDX2, whereas primary ovarian cancers are mostly (> 90%) positive for CK7 and negative for CK20 and CDX2 [11].…”

Section: Discussionmentioning

confidence: 99%

“…A preoperative diagnosis between primary ovarian cancer and metastatic tumor is important to determine treatment strategies, but often challenging and difficult [5]. Despite advancements in imaging modalities, including computed tomography (CT), positron emission tomography (PET), ultrasonography (US), and magnetic resonance imaging (MRI), the final diagnosis of ovarian malignancy depends on a histological examination, particularly the findings of immunohistochemical staining [6].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Giant ovarian tumor with colorectal cancer: suggestion concerning the need for colonoscopy screening in cases with large ovarian tumor—a report of three cases

et al. 2022

View full text Add to dashboard Cite

Background Patients with giant ovarian tumor often have severe symptoms, such as abdominal distention, and the tumor tends to grow rapidly; therefore, sufficient preoperative assessments are difficult to perform. It is not always easy to differentiate between primary and metastatic ovarian cancer, especially when the ovarian tumor is huge, since a precise diagnosis of ovarian tumor depends on the histopathological findings of the excised specimen. Although metastatic ovarian tumors account for over 20% of all malignant ovarian tumors, preoperative colonoscopy is not considered a routine examination before surgery for giant ovarian tumor. Case presentation We herein report 3 cases of giant (> 25 cm) ovarian tumor with colorectal cancer. All three patients visited the clinic with progressing abdominal distention, and were referred with primary ovarian malignancy. Case 1: Rectal tumor was suspected by a digital examination at the outpatient clinic, and rectal cancer was diagnosed preoperatively by colonoscopy. Computed tomography revealed a single-nodule liver tumor. Ovariectomy, rectal resection, and partial hepatectomy were performed. A histological examination revealed both primary mucinous ovarian carcinoma and rectal carcinoma with liver metastasis. Case 2: Initially, the ovarian tumor was diagnosed as primary carcinoma based on the histological findings of an incision biopsy at the previous hospital. Chemotherapy for ovarian cancer was administered without remission, and subsequently, the patient was referred to our hospital. Since the CEA level was high (142 ng/ml), colonoscopy was performed and cecal cancer was diagnosed. Ovariectomy and right colectomy were performed, and the ovarian tumor was histologically diagnosed as metastatic adenocarcinoma. Case 3: Initial ovariectomy was performed, and rectal cancer was suspected at intra-operative surveillance. Colonoscopy was performed after surgery, and rectal cancer was diagnosed. The ovarian tumor was diagnosed as metastatic adenocarcinoma. After six cycles of FOLFOX, rectal resection was performed. Conclusion Regrettably, two of three cases in the current series were not diagnosed with colorectal cancer at the start of treatment. This experience suggests that screening colonoscopy should be considered before treatment for every case of giant ovarian tumor.

show abstract

Krukenberg’s tumour unilateral giant metachronous of colonic origin – Case report

Cited by 2 publications

References 9 publications

Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report

Treatment of bilateral ovarian dysgerminoma with 11-year follow-up: A case report

Giant ovarian tumor with colorectal cancer: suggestion concerning the need for colonoscopy screening in cases with large ovarian tumor—a report of three cases

Contact Info

Product

Resources

About