L’anémie dans l’insuffisance cardiaque

Abassade, P.; Rabenirina, F.; Garçon, Philippe; Antakly, Y.; Cador, Romain

doi:10.1016/j.ancard.2009.09.001

Cited by 6 publications

(5 citation statements)

References 9 publications

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“…In our study, the prevalence of anaemia in HF was 42%, near to the 49% that was found in France by Abassade et al , 10 and lower than the 64.3% found by Kuule et al in Uganda. 11 In the literature, the prevalence of anaemia is variable, from 4 to 61%, with the majority of studies finding it between 18 and 20%.…”

Section: Discussioncontrasting

confidence: 50%

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Prevalence of anaemia among patients with heart failure at the Brazzaville University Hospital: cardiovascular topic

Ikama¹,

Nsitou²,

Kocko³

et al. 2015

CVJA

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SummaryBackgroundHeart failure (HF) is a frequent cause of hospitalisation in cardiology. Its prognosis depends on several risk factors, one of which is anaemia.ObjectivesWe aimed to determine the prevalence of anaemia in patients with heart failure, and evaluate its impact on their prognosis.MethodsThis article describes a cross-sectional study with prospective collection of data, carried out from 1 January to 31 December 2010 in the Department of Cardiology at Brazzaville University Hospital, Congo. Patients admitted for heart failure were included. Anaemia was defined as a haemoglobin level < 12 g/dl for men and < 11 g/dl for women.ResultsIn total, 130 men (47.8%) and 142 women (52.2%) were recruited, mean age 56.9 ± 16.5 years. The prevalence of anaemia was 42%. Average levels of haemoglobin were 9.4 ± 1.8 and 13.8 ± 4.9 g/dl for the anaemic (A) and non-anaemic (NA) patients, respectively (p = 0.0001). Two hundred and forty-nine patients (91.5%) were in NYHA functional class III–IV. Forty-seven patients (17.3%) were on oral anticoagulation and 15 (5.5%) were on aspirin. The average duration of hospital stay was 19.1 ± 16.7 days, without a significant difference between the A and NA groups (19.4 ± 12 vs 18.8 ± 13.8 days; p = 0.79, respectively). Total mortality rate was 17%, with a significant difference between the A and NA groups (26 vs 10%; p = 0.001).ConclusionThis preliminary study showed a high prevalence of anaemia in patients with heart failure, and it had a negative effect on the prognosis.

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Section: Discussioncontrasting

confidence: 50%

“… 6 , 8 In our study, the patients were relatively young, with an average of 57 years, in comparison with large series in developed countries, where the median age of patients was 70 years. 9 , 10 In Africa, very few studies have been conducted assessing anaemia in HF patients. 11 - 13 …”

Section: Discussionmentioning

confidence: 99%

Prevalence of anaemia among patients with heart failure at the Brazzaville University Hospital: cardiovascular topic

Ikama¹,

Nsitou²,

Kocko³

et al. 2015

CVJA

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“…This relationship has been reported by other studies, such as those conducted by Bolger and Abromeit [3] [4]. However, some studies, like the one by Abassad et al [5], have found differing results. Despite these discrepancies, all authors agree that there are multiple factors contributing to anemia in heart failure patients, including hemodilution, inflammation, iron deficiency, renal insufficiency, and medication toxicity [6] [7] [8] [9].…”

Section: Discussionsupporting

confidence: 81%

Aetiologic Factors of Anemia During Heart Failure in Brazzaville (The Republic of the Congo)

Ikama,

Memougame,

Makani

et al. 2023

WJCD

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To contribute to improving the management of patients with heart failure and anemia in Brazzaville, a prospective and descriptive study was conducted in the University Hospital of Brazzaville for nine months (January 1st to September 30, 2017). Included 57 patients hospitalized for left or global heart failure and presenting anemia. Anemia was defined by an haemoglobin level < 12 g/dL in men and <11 g/dL in women. Proportionings of the reticulocytes rate, serum iron, ferritin, erythrocyte sedimentation rate (ESR) and/or C-reactive protein (CRP), electrophoresis of proteins, and evaluation of renal function by glomerular filtration rate (GFR), as well as the treatments of heart failure, and the auxiliary therapeutic ones, in particular the antithrombotic drugs, allowed aetiologic research. They were 20 men (35%) and 37 women (65%), old on average of 59 ± 17 years. The average rate of haemoglobin was 11.4 ± 1.4 g/dL. Heart failure was de novo in 24 cases (42.1%), old in 33 cases (57.9%); it was global in 54 cases (94.7%).The maintenance treatment associated diuretics in 32 cases (97%), angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blocker (ARB) in 31 cases (94%), beta-blockers in two cases (6.1%), digoxin in four cases (12.1%), aspirin in five cases (15.1%) and anti-vitamin K in four cases (12.1%). Anemia was microcytic hypochromic in 30 cases (52.6%), normocytic normochromic in 20 cases (35.1%), and macrocytic normochromic in one case (1.7%). The main aetiologic factors were hemodilution in 46 cases (80.7%), renal insufficiency in 30 cases (52.3%), inflammation in 29 cases (50.8%), and iron deficiency in one case (1.7%). The HIV serology, carried out in 11 cases, was negative.

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“…This prevalence is similar to that found by Groenveld in the United States [4], 37.2%. It is lower than those reported in previous series by Ikama in the Republic of the Congo [2], Abassade in France [3] and Makubi in Tanzania [5], 42%, 49% and 57%, respectively. According to the literature, the prevalence of anemia in heart failure varies between 4% and 61% in most published studies [2] [3] [4] [5].…”

Section: Discussioncontrasting

confidence: 69%

Epidemiological and Prognostic Aspects of Anemia during Heart Failure in Brazzaville (The Republic of the Congo)

Ikama,

Memougame,

Oko

et al. 2023

WJCD

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To improve the management of patients with heart failure and anemia at the University Hospital of Brazzaville, a cross-sectional study of patients diagnosed with heart failure condition (left or global heart failure) was conducted over a period of nine months from January 1 to September 30, 2017. A total of 171 patients were included during the study period. Study participants were divided into two groups: Group A included patients with an additional anemic condition (n = 57) and Group NA patients without anemia (n = 114). Anemia was defined as a hemoglobin rate of < 12 g/dL for men and <11 g/dL for women. All eligible patients admitted to the Department of Cardiology were included in the study. The frequency of anemia was 33.3%, with a mean hemoglobin level of 9.4 ± 1.5 g/dL. Men accounted for 46.9% of cases (n = 79) and women 53.8% (n = 92). The mean age of eligible patients was 57.5 ± 16.5 years. Of these, 46.2% (n = 75) had a secondary educational level and 53.8% (n = 92) had a low socioeconomic status. Heart failure was global in 153 cases (89.5%). Patients were on NYHA III-IV functional class in 112 cases (65.5%), with a statistically significant difference between anemic and non-anemic patients (p = 0.0001). The main underlying heart diseases were dilated cardiomyopathy (75.1%), hypertensive heart disease (10.5%), ischemic heart disease (6.5%), and valvular disease (4.7%). The comparison between the two groups (A and NA) showed a longer hospital length of stay (18.4 ± 8.9 versus 12.9 ± 7.6 days; p = 0.00001) and a higher mortality rate (4 versus 2 deaths). The re-hospitalization rate was more important in group A (n = 4) than in group NA (n = 1). Anemia is a common condition in patients with heart failure. It worsens the clinical features and prognosis.

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L’anémie dans l’insuffisance cardiaque

Cited by 6 publications

References 9 publications

Prevalence of anaemia among patients with heart failure at the Brazzaville University Hospital: cardiovascular topic

Prevalence of anaemia among patients with heart failure at the Brazzaville University Hospital: cardiovascular topic

Aetiologic Factors of Anemia During Heart Failure in Brazzaville (The Republic of the Congo)

Epidemiological and Prognostic Aspects of Anemia during Heart Failure in Brazzaville (The Republic of the Congo)

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