“…The worldwide distribution of Yersinia enterocolitica and the life-threatening prognosis of septicemia due to this species in compromised hosts (24,28,32,34) make investigations into the activity of new antibiotics mandatory. Y. enterocolitica appears to be susceptible to a wide range of antibiotics, especially aminoglycosides and tetracyclines, but the entire species exhibits some degree of resistance to ampicillin, cephalothin, and related ,B-lactam antibiotics because of the synthesis of P-lactamases (5,6,11,13,15,16,31,40).…”