2018
DOI: 10.1590/0001-3765201820170352
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L-carnitine supplementation in the recovery of plasma L-carnitine in patients with heart failure submitted to coronary artery bypass grafting

Abstract: Coronary artery bypass grafting reduces plasma L-carnitine and may impair the production of myocardial energy. L-carnitine supplementation may elevate plasma L-carnitine and increase cardiac mechanical efficiency. The objective of this study was to verify the recovery of preoperative plasma LC in patients with heart failure undergoing coronary artery bypass grafting supplemented with a daily oral dose of 50 mg / kg. Volunteers with ischemic heart failure who underwent surgery were randomized into a supplemente… Show more

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“…Many in vitro studies [22][23][24][25][26][27][28][29], and in vivo studies of animals [30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47] and humans [48][49][50][51][52][53][54][55][56][57][58][59] have reported different beneficial functions for carnitine. In the following, the main activities observed are reported.…”
Section: An Updated Shot Of Beneficial Properties: In Vitro and In Vivo Studiesmentioning
confidence: 99%
“…Many in vitro studies [22][23][24][25][26][27][28][29], and in vivo studies of animals [30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47] and humans [48][49][50][51][52][53][54][55][56][57][58][59] have reported different beneficial functions for carnitine. In the following, the main activities observed are reported.…”
Section: An Updated Shot Of Beneficial Properties: In Vitro and In Vivo Studiesmentioning
confidence: 99%