Ever since the United Nations Convention on the Rights of Persons with Disabilities took place in 2006, the promotion of fundamental rights for this group has been continuous, fostering social inclusion to reduce the stereotypes and prejudices that had prevailed until that time. The aim of this research is to analyse the discourse on social networks of the main associations, foundations, as well as public and private organisations with regard to disability in Spain on the International Day of Persons with Disabilities 2020, in order to identify the topics that generate the highest level of interaction among the different profiles on social networks. The results suggest that despite the limited reach of these organisations on social networks, their discourse is based on fundamental rights such as participation and inclusion, accessibility, individual autonomy, and equal opportunity, which provide greater knowledge and a positive vision of persons with disabilities to society as a whole, raising awareness about stereotypes, prejudices and hate speech that are still common.