La epidemiología del dengue y del dengue hemorrágico en Santiago de Cuba, 1997

Dinámica epidemiológica del dengue en Isla de Pascua

“…Ya existe cierta preocupación por la existencia de tres casos por DENV-4 en 2009. En Cuba en 1981 ocurrió una gran epidemia de dengue hemorrágico (por DENV-2) de miles de casos, a continuación de la epidemia de dengue clásico (por DENV-1) en 1977-78 54 y un rebrote en 1997 55 . Desde la perspectiva teórica, la primera epidemia debió afectar a 94% de la población (aproximadamente 3.500 casos); sin embargo, se notifi caron 639 lo que sugiere sub-notifi cación y gran cantidad de casos sub-clínicos.…”

The dengue and dengue hemorrhagic fever epidemic in Puerto Rico, 1994-1995.

“…In contrast, our finding of constant disease severity throughout the epidemic (as opposed to recent reports from Australia and Cuba, but not French Polynesia) is probably due to our surveillance system's prolonged history, with stable data sources and case definitions, and our ability to provide a laboratory-based diagnosis for large numbers of cases. [35][36][37] It is therefore less subject to reporting bias (for example, less frequent dengue reporting at the beginning of an epidemic, or preferential reporting of the most severe cases as the epidemic progresses).…”

Neutralizing Antibodies after Infection with Dengue 1 Virus

“…ELISA results showed no evidence of acute dengue infection. To avoid analyzing serum from persons infected by any other DENV, we excluded samples from Santiago de Cuba province because of the DENV-2 epidemic that occurred in 1997 ( 19 , 20 ). …”