La pancréatite lupique : une série de six cas

Dhaou, B. Ben; Aydi, Z.; Boussema, F.; Dahmen, F. Ben; Baïli, L.; Ketari, S.; Cherif, O.; Rokbani, L.

doi:10.1016/j.revmed.2012.07.001

Cited by 12 publications

(7 citation statements)

References 34 publications

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“…The pathogenesis of AP is multifactorial, and several etiologies are often incriminated like ischemic mechanism due to vasculitis or thrombosis related to an associated antiphospholipid antibody syndrome, autoimmune mechanism, or drug injury induced by corticosteroids and azathioprine or an intercurrent infectious disease 8 . In our patient, AP was related to the SLE regarding immunological pertubances with concomitant multiorgan manifestations and after excluding frequent etiologies.…”

Section: Discussionmentioning

confidence: 71%

Systemic lupus erythematosus‐related acute pancreatitis: An exceptional form with severe exocrine and endocrine pancreatitic failure in a Tunisian child

Ferjani

Euch

Hammi

et al. 2022

Clinical Case Reports

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Acute pancreatitis may be the first manifestation in systemic lupus erythematosus or occur during evolution. It is a rare complication, which is often associated with other visceral manifestations. Outcome is usually favorable but can be serious. We report a case of a 17‐year‐old girl with a past history of systemic lupus erythematosus who developed acute pancreatitis revealed by abdominal pain. Elevated serum amylase and lipase levels and pancreatic enlargement on tomography confirmed the diagnosis. Although high‐dose corticosteroid was prescribed, the patient died from a refractory diabetic ketoacidosis.

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Section: Discussionmentioning

confidence: 71%

Systemic lupus erythematosus‐related acute pancreatitis: An exceptional form with severe exocrine and endocrine pancreatitic failure in a Tunisian child

Ferjani

Euch

Hammi

et al. 2022

Clinical Case Reports

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“…The incidence of lupus pancreatitis is between 0.4 and 1.1 cases per 1000 lupus cases per year [10]. Lupus pancreatitis is thought to be caused by global multisystemic inflammation, such as vasculitis, immune complex deposition, microthrombi, and vascular intimal thickening, and ischemia [11]. T-cell infiltration and complement activation are also possible causes of pancreatitis seen in SLE [12].…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Systemic Lupus Erythematosus in a Polynesian Male with a History of Rheumatic Fever: A Case Report and Literature Review

Diaz

Lim

Liu

et al. 2018

Case Reports in Pediatrics

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The presence of rheumatic heart disease (RHD) and systemic lupus erythematosus (SLE) has rarely been described in one patient. This report describes an adolescent Polynesian male with RHD who developed SLE years later. Initially, he fulfilled modified Jones criteria for rheumatic fever with aortic insufficiency, transient arthritis, elevated streptococcal titers, and a high erythrocyte sedimentation rate with a negative antinuclear antibody (ANA). He responded well to nonsteroidal anti-inflammatory and penicillin prophylaxis, which supported the diagnosis of rheumatic fever. Five years after his RHD diagnosis, he developed pancreatitis with glomerulonephritis, nephrosis, and pancytopenia. In addition, laboratory results revealed that he had multiple autoantibodies: anti-Sm and extremely elevated anti-dsDNA and ANA, fulfilling diagnostic criteria for SLE. The patient was treated, and he responded to pulse steroids followed by oral steroid therapy. To our knowledge, there are no known reported cases of a patient who was diagnosed with both RHD and SLE and met the clinical criteria for both diseases. The rarity of this concurrent disease process in one patient suggests a possible overlap in humoral immunity toward self-antigens as well as ethnic variability that increases predisposition to rheumatologic diseases.

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“…AP occurs in 1%-8% of SLE patients and is proposed to be the result of vascular damage. [7] The diagnosis of SLE-related pancreatitis requires the exclusion of more common causes for pancreatitis, as well as evidence of increased disease activity. The treatment for SLE-associated AP includes the standard care for pancreatitis, however, immunomodulatory drugs are necessary in order to control the underlying SLE.…”

Section: Discussionmentioning

confidence: 99%

UnMASking the diagnosis: Acute severe necrotizing pancreatitis in the setting of systemic lupus erythematosus complicated by macrophage activation syndrome

Askin

Edelson

Dooley

et al. 2018

CRIM

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Systemic lupus erythematosus (SLE) is a common rheumatologic condition with known GI involvement. Acute pancreatitis (AP) is a rare GI complication of SLE and is typically associated with increased disease activity. Macrophage activation syndrome (MAS) is an unusual, hyper-inflammatory response to a rheumatologic stimulus characterized by hyperferritinemia, pancytopenia, thermal dysregulation and multi-organ dysfunction. MAS, more commonly seen in children, has been reported to complicate both adult onset SLE and AP. We present a case of necrotizing AP secondary to an SLE flare complicated by MAS in an adult patient successfully treated with anakinra.

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La pancréatite lupique : une série de six cas

Cited by 12 publications

References 34 publications

Systemic lupus erythematosus‐related acute pancreatitis: An exceptional form with severe exocrine and endocrine pancreatitic failure in a Tunisian child

Systemic lupus erythematosus‐related acute pancreatitis: An exceptional form with severe exocrine and endocrine pancreatitic failure in a Tunisian child

Diagnosis of Systemic Lupus Erythematosus in a Polynesian Male with a History of Rheumatic Fever: A Case Report and Literature Review

UnMASking the diagnosis: Acute severe necrotizing pancreatitis in the setting of systemic lupus erythematosus complicated by macrophage activation syndrome

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