Label-Free Detection of Chikungunya Non-Structural Protein 3 Using Electrochemical Impedance Spectroscopy

George, Ankitha; Amrutha, M. S.; Srivastava, Priyanshu; Sai, V. V. R.; Sunil, Sujatha; Ramanathan, Surash

doi:10.1149/2.1081914jes

Cited by 29 publications

(11 citation statements)

References 56 publications

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“…In recent years, electrochemical biosensor has become a reliable analytical equipment [ [146] , [147] , [148] ], which can detect various viruses that threaten human health [ [149] , [150] , [151] ]. Electrochemical biosensor is a kind of equipment which has both electrochemical sensing and biosensor [ 152 , 153 ].…”

Section: Detection Methodsmentioning

confidence: 99%

Current methods and prospects of coronavirus detection

Deng

Liu

et al. 2021

Talanta

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Section: Detection Methodsmentioning

confidence: 99%

Current methods and prospects of coronavirus detection

Deng

Liu

et al. 2021

Talanta

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“…SAM was activated by N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hy-drochloride (EDC) and N-hydroxysuccinimide (NHS) to form NHS ester. As a result, impedance decrease effectively ( George et al, 2019 ). It should not be left unmentioned that the study is consistent with previously reported literature ( Radhakrishnan et al, 2016 ).…”

Section: Electrochemical Biosensors For Virus Detectionmentioning

confidence: 99%

Ultrasensitive detection of pathogenic viruses with electrochemical biosensor: State of the art

Khan¹,

Hasan

Hossain

et al. 2020

Biosensors and Bioelectronics

177

108

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Last few decades, viruses are a real menace to human safety. Therefore, the rapid identification of viruses should be one of the best ways to prevent an outbreak and important implications for medical healthcare. The recent outbreak of coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus which belongs to the single-stranded, positive-strand RNA viruses. The pandemic dimension spread of COVID-19 poses a severe threat to the health and lives of seven billion people worldwide. There is a growing urgency worldwide to establish a point-of-care device for the rapid detection of COVID-19 to prevent subsequent secondary spread. Therefore, the need for sensitive, selective, and rapid diagnostic devices plays a vital role in selecting appropriate treatments and to prevent the epidemics. During the last decade, electrochemical biosensors have emerged as reliable analytical devices and represent a new promising tool for the detection of different pathogenic viruses. This review summarizes the state of the art of different virus detection with currently available electrochemical detection methods. Moreover, this review discusses different fabrication techniques, detection principles, and applications of various virus biosensors. Future research also looks at the use of electrochemical biosensors regarding a potential detection kit for the rapid identification of the COVID-19.

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“…In addition, commercial immunochromatography antigen detection kits are gaining popularity in the recent past owing to their high sensitivity and specificity with no cross-reactivity with other arboviruses ( Okabayashi et al, 2015 ; Jain et al, 2018a ). Other diagnostic initiatives are the use of biosensors using different technologies such as electrochemical impedance spectrometry and optical fibers that have shown promise in CHIKV diagnosis ( George et al, 2019 , 2021 ).…”

Section: Laboratory Diagnosismentioning

confidence: 99%

Current Status of Chikungunya in India

Sunil¹

2021

Front. Microbiol.

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Chikungunya fever (CHIKF) is an arbovirus disease caused by chikungunya virus (CHIKV), an alphavirus of Togaviridae family. Transmission follows a human-mosquito-human cycle starting with a mosquito bite. Subsequently, symptoms develop after 2–6 days of incubation, including high fever and severe arthralgia. The disease is self-limiting and usually resolve within 2 weeks. However, chronic disease can last up to several years with persistent polyarthralgia. Overlapping symptoms and common vector with dengue and malaria present many challenges for diagnosis and treatment of this disease. CHIKF was reported in India in 1963 for the first time. After a period of quiescence lasting up to 32 years, CHIKV re-emerged in India in 2005. Currently, every part of the country has become endemic for the disease with outbreaks resulting in huge economic and productivity losses. Several mutations have been identified in circulating strains of the virus resulting in better adaptations or increased fitness in the vector(s), effective transmission, and disease severity. CHIKV evolution has been a significant driver of epidemics in India, hence, the need to focus on proper surveillance, and implementation of prevention and control measure in the country. Presently, there are no licensed vaccines or antivirals available; however, India has initiated several efforts in this direction including traditional medicines. In this review, we present the current status of CHIKF in India.

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Label-Free Detection of Chikungunya Non-Structural Protein 3 Using Electrochemical Impedance Spectroscopy

Cited by 29 publications

References 56 publications

Current methods and prospects of coronavirus detection

Current methods and prospects of coronavirus detection

Ultrasensitive detection of pathogenic viruses with electrochemical biosensor: State of the art

Current Status of Chikungunya in India

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