Label-free electrochemical immunosensor based on gold–silicon carbide nanocomposites for sensitive detection of human chorionic gonadotrophin

Recent advances in biosensor development for the detection of cancer biomarkers

“…One immuno-sensor used amino capped platinum porous nanoparticles whereas, the other exploited biofunctional carboxyl graphene nanosheets as signal probes for making a highly stable biosensor Wang et al, 2014b). Apart from these, other electrochemical cancer biosensors for protein biomarkers detection are also reported Rezaei et al, 2011;Viswanathan et al, 2012;Yang et al, 2014). Mukundan et al (2009) have developed a fluorescence-based sandwich detection method for the measurement of CEA, a molecule associated with multiple cancer types.…”

Concave gold nanoparticle-based highly sensitive electrochemical IgG immunobiosensor for the detection of antibody–antigen interactions

“…[9][10][11] However, these methods oen suffer from considerable time consumption, high cost and tediously professional operation, which make them imperfect candidates for practical applications and demand a more convenient detection method with a comparable or even higher sensitivity. 15,16 Antibodies are large Y-shaped protein molecules produced by the immune system, which are typically used to identify and neutralize foreign objects such as bacteria and viruses. 15,16 Antibodies are large Y-shaped protein molecules produced by the immune system, which are typically used to identify and neutralize foreign objects such as bacteria and viruses.…”

Immunoassay for netrin 1 via a glassy carbon electrode modified with multi-walled carbon nanotubes, thionine and gold nanoparticles

“…Therefore, to explore a new method with high sensitivity, good selectivity and simplicity is of great importance and urgency. Electrochemical immunosensors, based on the special reaction between antibodies and antigens, with the characteristics of simplicity, facility, rapidity, sensitivity and real-time quantification have attracted more and more attention, and widely applied to detect various cancer markers [9][10][11]. Given these advances, we intend to develop a novel and effective immunosensor as a promising tool to sensitively and accurately determine netrin1in serum.…”