Laboratoriumserfahrungen mit einer Kombination von Trimethoprim und Sulfamethoxazol

Legler, F

doi:10.1055/s-0028-1108340

Cited by 3 publications

(3 citation statements)

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“…29% sensitivity) lie in the middle of the reported range [8,17]. The results with Proteus are more uniform: in general there is a sensitivity rate of about 80% [10][11][12], The determina tion of the MIC is less often performed. In this respect, our results are in good agreement with other authors.…”

Section: Resultsmentioning

confidence: 70%

On the Sensitivity of Pseudomonas and Proteus to the Combination of Trimethoprim and Sulphamethoxazole

Ritzerfeld¹,

Hasch²

1972

Chemotherapy

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The activity of the combined preparation of trimethoprim and sulphamethoxazole against 152 strains of Pseudomonas and 348 strains of Proteus was investigated. In the disc diffusion test, 29.3% of the Pseudomonas and 94.8% of the Proteus strains were in the sensitive or moderately sensitive regions. The MIC, as determined by the plate dilution test, was found to be 2.5 μg/ml TMP and 50 μg/ml SMZ for 9.2% of the Pseudomonas and 87.4% of the Proteus strains. Comparison of the activity of the individual components with that of the combination showed the combination to be superior.

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Section: Resultsmentioning

confidence: 70%

On the Sensitivity of Pseudomonas and Proteus to the Combination of Trimethoprim and Sulphamethoxazole

Ritzerfeld¹,

Hasch²

1972

Chemotherapy

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“…The exact cause of IPP has not been definitively identified 10 . Papillomavirus and Psittacid Herpesvirus-1 have been suggested as some of the ethiologic agents of IPP 11 12 13 . There are also some cases of papillomatosis described in passerines such as finches and canaries 14 15 .…”

Section: Discussionmentioning

confidence: 99%

Laryngeal and oropharyngeal adenocarcinoma with pulmonary metastases in a common raven (Corvus corax)

Westhoff,

Fischer,

Jäger

et al. 2024

Tierarztl Prax Ausg K Kleintiere Heimtiere

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A captive 15-year-old male common raven (Corvus corax) was presented for post-mortem examination. It had been previously presented to a local veterinarian due to a 3–4 weeks long history of abnormal respiratory sounds. Upon admission, the bird demonstrated severe dyspnea and a massive amount of mucous in the oropharynx. After symptomatic treatment, dyspnea deteriorated dramatically, and euthanasia was elicited because of poor prognosis. The necropsy revealed a 2.65 x 2.15 x 2.18 cm expansile and poorly delineated cauliflower-shaped mass around the glottis and extending inside the tracheal lumen. Additionally, a dilated salivary gland in the adjacent tissue and multifocal reddish-fleshy areas in the lung parenchyma were detected. Histopathological examination identified the mass as moderately differentiated, tubular adenocarcinoma with invasive growth and moderate to marked cellular atypia and numerous mitoses. The presumptive origin of the neoplasia was one of the salivary glands. Multiple metastases were identified in the lung both macroscopically and histologically. Bacterial culture and molecular testing for West Nile and Usutu viruses were negative. To the authors’ knowledge, this is the first report of metastatic laryngeal and oropharyngeal adenocarcinoma in a common raven.

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“…A comparison of all combinations of the different concentrations used shows that SMZ + TMP is in 1 case and SDZ + TMP in 4 cases more effective against the 13 species or genera tested than the other combinations. SMZ and SDZ were equally effective in synergistic action (as shown by the FIC indices) against the various kinds of bacteria.The combination of sulfamethoxazole (SMZ) and trimethoprim (TMP) has been shown both in vitro [1,2,9,11,12] and in vivo [1,4,5,13,15] to produce conspi cuous mutual synergism in antibacterial ef fect, even if the organism is resistant to sul fonamide alone. This combination is well known as cotrimoxazole (SMZ + TMP).…”

mentioning

confidence: 99%

A Comparison of the <i>in vitro</i> Activities of Sulfamethoxazole and Sulfadiazine Combinations with Trimethoprim

Js¹

1979

Chemotherapy

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The sensitivity of 125 strains of 13 species or genera of bacteria to sulfamethoxazole (SMZ), sulfadiazine (SDZ), trimethoprim (TMP), SMZ + TMP and SDZ + TMP was determined by means of trays. A comparison of all combinations of the different concentrations used shows that SMZ + TMP is in 1 case and SDZ + TMP in 4 cases more effective against the 13 species or genera tested than the other combinations. SMZ and SDZ were equally effective in synergistic action (as shown by the FIC indices) against the various kinds of bacteria.

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Laboratoriumserfahrungen mit einer Kombination von Trimethoprim und Sulfamethoxazol

Cited by 3 publications

References 0 publications

On the Sensitivity of Pseudomonas and Proteus to the Combination of Trimethoprim and Sulphamethoxazole

On the Sensitivity of Pseudomonas and Proteus to the Combination of Trimethoprim and Sulphamethoxazole

Laryngeal and oropharyngeal adenocarcinoma with pulmonary metastases in a common raven (Corvus corax)

A Comparison of the <i>in vitro</i> Activities of Sulfamethoxazole and Sulfadiazine Combinations with Trimethoprim

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