Lack of Correlation Between Urinary Iodine and Dietary Iodine in Goitrous Children

Vought, R. L.; Maisterrena, J; Tovar, Enrique; London, William T.

doi:10.1210/jcem-25-4-551

Cited by 4 publications

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“…A quantidade de iodo excretado por grama de creatinina em uma amostra urinária é representativa do total urinário excretado, desde que a excreção renal de creatinina não sofra grandes flutuações (20)(21)(22)(23). Apesar da creatinúria ter sido avaliada por nós, nas mesmas amostras, a relação iodúria/creatinúria não foi utilizada pois o coeficiente dessa relação não foi menor que a concentração de iodo urinário isolada (24).…”

Section: Methodsunclassified

Correlação entre níveis de iodúria e TSH colhido em cordão umbilical de recém-nascidos do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, São Paulo

Alves

Maciel

Kunii

et al. 2005

Arq Bras Endocrinol Metab

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Correlation Between Urinary Iodine Levels and TSH of Umbilical Cord fromNewborns of the University Hospital at the School of Medicine from Ribeirão Preto, São Paulo. The safest and most efficient way to diagnose congenital hypothyroidism (CH) is through screening programs using serum thyroid stimulating hormone (TSH). CH occurs in one in 1:2,300 -1:5,000 births but higher rates are found in iodine-deficient areas. Iodine was measured in the urine of 141 newborns (87 males and 54 females) from Ribeirão Preto to complement the screening program developed by the School of Medicine of Ribeirão Preto (FMRP-USP) and Federal University of São Paulo (UNIFESP). TSH values did not disclose any case of CH, although we have seen an elevated ratio (0.96%) of calls for retests. The iodine urinary levels ranged from 2.1 to 194µg/l (mean 58.3±36.2µg/l). No differences between the levels of urinary iodine and gender or gestational ages were observed. A negative correlation between urinary iodine and TSH of blood from umbilical cord was found (r= -0.20, p= 0.02).

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Section: Methodsunclassified

Correlação entre níveis de iodúria e TSH colhido em cordão umbilical de recém-nascidos do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, São Paulo

Alves

Maciel

Kunii

et al. 2005

Arq Bras Endocrinol Metab

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Pattern of urinary iodine excretion in children

Manjari

Rajashree

Anagha

et al. 1992

Indian J Clin Biochem

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Endemic goiter and cretinism. Naturally occurring goitrogens

Delange¹,

Ermans²

1976

Pharmacology & Therapeutics. Part C: Clinical Pharmacology

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This conclusion rests on substantial data which may be summarized as foUows: (a) Dietary iodine supply is low in most goiter endemias because of poorly-iodinated soil (Hercus et al, 1925). This situation is found in régions which remained longest under the quaternary glaciers and which lost most of the iodine from their soil when the ice thawed (Merke, 1965; Kelly and Snedden, 1960). A rigorous assessment of the iodine content of foods is extremely difficult to make for methodological reasons (

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Lack of Correlation Between Urinary Iodine and Dietary Iodine in Goitrous Children

Cited by 4 publications

References 0 publications

Correlação entre níveis de iodúria e TSH colhido em cordão umbilical de recém-nascidos do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, São Paulo

Correlação entre níveis de iodúria e TSH colhido em cordão umbilical de recém-nascidos do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, São Paulo

Pattern of urinary iodine excretion in children

Endemic goiter and cretinism. Naturally occurring goitrogens

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