Lactic and Malic Dehydrogenase Activities and Isoenzyme Patterns in Blood Sera of Developing Neonatal Piglets

Karlsson, Börje W.

doi:10.1159/000240131

Cited by 6 publications

(2 citation statements)

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“…Within the first day after birth the concentration increases from 24 to 72 mg/ml. After the second day the concentra tion decreases and is about 65 mg/ml 20 days after birth-compared to 96 mg/ml in adult pig serum (Karlsson, 1968).…”

Section: Levels O F Total Protein In Fetal and Neonatal Pig Serummentioning

confidence: 86%

“…It has been shown in the pig that marked changes occur in the concentration of AFP, albumin and total serum proteins during the neonatal period (Karlsson, 1968(Karlsson, , 1970. In most animal species the concentration of AFP decreases successively after birth (Ruoslahti and Seppald, 1972;Sell et al, 1974;Gitlin, 1975), whereas the pig shows increased levels of AFP (Karlsson, 1970).…”

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confidence: 99%

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Synthesis of α-Fetoprotein, Albumin and Total Serum Protein in Neonatal Pigs

Ingvarsson¹,

Carlsson²,

Karlsson³

1978

Neonatology

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Studies on the incorporation of ³H-leucine established that synthesis of α-fetoprotein (AFP) does occur in the neonatal pig. This synthesis probably accounts for the increase in AFP concentration from 0.46 mg/ml on the day after birth to the maximum value of 1.02 mg/ml found 5 days after birth. After the 5th day, the concentration decreases successively and AFP cannot be detected by electroimmunoassay in the sera of 8-week-old pigs. During the first 3 weeks of extrauterine life, the albumin concentration in serum increases from 3 mg/ml to approximately 30 mg/ml due mainly to increased synthesis of albumin. The concentration of AFP in the fetal pig serum decreases from 3 mg/ml at 6.5 cm crown-to-rump (CR) length to 0.8 mg/ml at 28 cm CR length, whereas the albumin concentration increases from 0.2 mg/ml at 6.5 cm CR length to 1.0 mg/ml at 28 cm CR length. The total serum protein content in the fetus is approximately 20 mg/ml irrespective of gestational age. During the first day after birth there is a marked increase in both the synthesis and the concentration of total serum proteins. The concentration rises to 70 mg/ml during the first day and then slowly declines to 65 mg/ml during the 3 weeks following birth.

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Section: Levels O F Total Protein In Fetal and Neonatal Pig Serummentioning

confidence: 86%

mentioning

confidence: 99%