Lactococcus garvieae Endocarditis with Initial Presentation of Acute Cerebral Infarction in a Healthy Immunocompetent Man

Abstract

Abstract

Meningitis caused by Lactococcus garvieae

“…6 Since an increasing number of human infections due to L. garvieae have been reported in recent times, this organism has gained recognition as an emerging zoonotic pathogen. [2][3][4][5][6] One probable reason for its increasing reports might be availability of advanced bacterial identification techniques. A total of 21 cases of L. garvieae with clinical details have been reported in the literature 7 ; most of which were suffering from endocarditis.…”

“…because of its morphological and biochemical similarities. 4 In this case report, we describe a rare case of meningitis caused by L. garvieae, in the absence of endocarditis, in an immunocompetent patient, who presented as a suspected case of posterior circulation stroke with no past history of contact with raw fish.…”

An Overview of Virulence-Associated Factors of Gram-Negative Fish Pathogenic Bacteria

“…The data obtained in this study suggest that plp constitutes a negative regulator of the haemolysin genes vah1 and llpA and that vah1 plays a role in the pathogenicity of this bacterium. A repeat-in-toxin (RTX) gene cluster (rtxACHBDE) related to haemolysis in L. anguillarum was identified by Li et al (2008) a few years later. Haemolytic-deficient mutant strains were obtained by interrupting vah1 and an rtx gene, leading to the conclusion that the rtx gene cluster represents a new haemolytic mechanism in L. anguillarum.…”

Lactococcus garviae Endocarditis: Case Report

“…Laboratuvar tetkiklerinde beyaz kan hücreleri 12530 mm 3 , nötrofil %81, C-reaktif protein (CRP) 260 mg/L, sedimentasyon hızı 75 mm/saat saptandı. Hastadan altı saat aralıklarla ikişer set kan kültürü alındıktan sonra ampirik antibiyoterapi başlandı; penisilin allerjisi nedeni ile vankomisin 2x1 g, gentamisin 3x80 mg ve rifampisin 600 mg/gün olarak düzenlendi.…”