“…Medium risk of bias was found for over 2/3 of the studies (22/32, 68.7%) [ 3 , 4 , 6 , 7 , 12 , 21 , 26 – 28 , 34 , 41 , 46 , 49 , 61 , 69 , 80 , 86 , 90 – 92 , 96 , 101 ], 4/32 (12.5%) were of high methodological quality [ 10 , 62 , 78 , 79 ] and 6/32 studies (18.8%) were of low quality [ 39 , 72 , 81 , 82 , 89 , 109 ] (Supplementary Tables S 1 -S 3 ). The main reasons for a medium to low methodological quality were due to unclear description of participants and/or prior interventions.…”