In recent decades in the Mediterranean basin there has been a considerable increase in both the number of wildfires and the extent of fire-damaged areas, resulting in ecological and socio-economic impacts. Protected areas are particularly vulnerable and many characteristics underpinning their legal protection are threatened. Several studies have been devoted to mitigating wildfire risks inside the protected areas, however often only in regard to natural heritage losses. Based on the adaptive wildfire resilience approaches, this work proposes a framework of actions that integrates natural, social and economic components. Starting from the Vesuvius National Park case study, affected by wildfires in 2017, the paper proposes a framework of action, envisaging two main phases: (i) the identification of priority intervention areas, by means of spatial multicriteria decision analysis, and (ii) damage assessment by using a monetary approach to value ecosystem services (ESs). The results identified priority areas where to concentrate economic and material resources, and estimated ecosystems damage, demonstrated ESs losses in areas adjacent to the burnt ones. This work, by integrating the relation between environmental sciences and policy, underpins a medium-long term development planning process. The aim of this work is to support landscape management and planning that includes socio-economic components such as sustainable development measures.