The drilling during Ocean Drilling Program Leg 146 at the accretionary margin complexes off Vancouver Island, Canada (VIM), and Oregon, U.S.A (COM), addressed specific geochemical relationships and phenomena associated with fluid, gas, and heat fluxes generated by the compressive forces. Of particular importance were the occurrence of hydrates and formation of thermogenic hydrocarbons. In most cases, the geochemistry of the hemipelagic sediments is dominated by steady-and nonsteady-state diagenetic reactions, including sulfate reduction (Sites 888 and 891), and methanogenesis and methanotrophy (Sites 888-892). However, these shallow (<600 mbsf) sediments are also clearly and extensively influenced by pervasive and active fracture COM migration of deeper seated thermogenic hydrocarbons at the VIM and COM, respectively. The origin of bacterial and thermogenic gases is confirmed by their molecular and stable carbon isotope signatures. In many cases, the occurrence of C 2 + hydrocarbons delineates the fault zones.Only disseminated macrocrystalline hydrate, not massive hydrate, was encountered during Leg 146. Based on the carbon isotope signature, the hydrate is of bacterial origin and identical to that of the surrounding sediment free gas. Thermogenic gas hydrates were not encountered. The discrepancy between the location of the bottom-simulating reflector (BSR) and the base of hydrate stability may be caused by the presence of other gases or fluid constituents in the hydrate lattice. The amount of free gas inferred by the vertical seismic profiler (VSP) below the BSR may be due to the incomplete upward cryo-distillation of gases. This vertical shift could be created by (1) the change in bottom-water temperatures between glacial and interglacial, and (2) a pressure drop caused by sea-level change and accretionary uplift. The presence of hydrogen sulfide in the methane hydrates at Site 892 was unexpected and results from the rapid incorporation of H 2 S into hydrates, protecting them from reaction, (e.g., formation of iron monosulfides.)