Lansium domesticum—A Fruit with Multi-Benefits: Traditional Uses, Phytochemicals, Nutritional Value, and Bioactivities

Abstract

Lansium domesticum (Langsat, Meliaceae) is a tropical fruit mainly found in Southeast Asian countries, particularly in Thailand, Malaysia, Indonesia, and the Philippines. Traditionally, it is utilized as a folk treatment for eye inflammation, ulcers, diarrhea, dysentery, fever, spasms, flatulence, worms, insect bites, scorpion stings, and malaria. Additionally, it is utilized as a mosquito repellent, skin moisturizer and whitening agent. Pharmacological research showed that the plant has a wide array of bioactivities, including antimalarial, antifeedant, anti-aging, wound healing, antioxidant, cytotoxic, analgesic, antibacterial, antimutagenic, insecticidal, and larvicidal. The most commonly described activities were attributed to the presence of terpenoids and phenolics. Further, some studies reported the preparation of nanoparticles and pharmaceutical formulations from the plant. This review highlights the potential of L. domesticum as herbal medicine. It provides an overview about the reported data on L. domesticum from 1931 to November 2021, including nutritional value, traditional uses, phytoconstituents, and bioactivities, as well as nanoparticles and pharmaceutical formulations.

Comparative proteomics reveals anticancer compounds from Lansium domesticum against NSCLC cells target mitochondrial processes

“…In the underivatized fraction LH6-6, spathulenol, cadinol, and isoaromadendrene were detected; these compounds were previously detected in L. domesticum in fractions that are antifungal. 17,18 Likewise, in the underivatized LH7-6 fraction, cadinol was found and similarly detected in previous reports. 18 In our previous LC-MS/MS analysis, we reported that L. domesticum hexane fraction contained primarily of phenylpropanoids and polyketides (80.71%) and lipids and lipid-like molecules (18.78%).…”

“…On the other hand, the derivatized fractions yielded fatty acids, monoglycerides, and some sterols. In the underivatized fraction LH6‐6, spathulenol, cadinol, and isoaromadendrene were detected; these compounds were previously detected in L. domesticum in fractions that are antifungal 17,18 . Likewise, in the underivatized LH7‐6 fraction, cadinol was found and similarly detected in previous reports 18 .…”

KARAKTERISASI SENYAWA ASAM LEMAK PADA AKAR TUMBUHAN LANGSAT (Lansium domesticum Correa) (CHARACTERIZATION OF FATTY ACID COMPOUNDS IN THE ROOT OF LANGSAT PLANT (Lansium domesticum Correa)

“…Famili ini memiliki sekitar 600 spesies dan 53 genus yang tersebar luas di daerah tropis maupun subtropis [1] . Lansium domesticum yang dikenal sebagai langsat adalah tumbuhan tropis yang banyak ditemukan di Asia Tenggara, khususnya di Thailand, Malaysia, Indonesia, dan Filipina [2] .…”

Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of Carpesium abrotanoides L. (Asteraceae)

“…It was also reported that more than 80% of people worldwide rely on traditional medicines as a primary source of healthcare, involving the utilization of plant extracts or their phytoconstituents [4]. Recently, plantderived metabolites have become greatly important due to their structural diversity and promising bioactivities [5][6][7]. utilized for bruises, bronchitis, and hepatitis [16].…”