Laparoscopic Nissen versus Toupet fundoplication: objective and subjective results of a prospective randomized trial

Koch, Oliver; Kaindlstorfer, Adolf; Antoniou, Stavros A.; Asche, Kai Uwe; Granderath, Frank A.; Pointner, Rudolph

doi:10.1007/s00464-011-1889-5

Cited by 46 publications

(29 citation statements)

References 34 publications

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“…Data from studies of patients with typical reflux symptoms demonstrate that laparoscopic fundoplication is highly effective in reducing the numbers of reflux events detected by pH/impedance [54] and produces symptomatic improvement comparable to PPI treatment [55]. Responses are poorer in patients with atypical symptoms, normal acid exposure and symptoms refractory to PPI treatment [56].…”

Section: Jaclyn a Smith Against The Motionmentioning

confidence: 99%

A Causal Relationship Between Cough and Gastroesophageal Reflux Disease (GERD) has been Established: A Pro/Con Debate

Kahrilas

Smith

Dicpinigaitis

2013

Lung

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Along with upper airway cough syndrome (formerly, postnasal drip syndrome) and eosinophilic airway inflammation (asthma, non-asthmatic eosinophilic bronchitis), gastroesophageal reflux disease (GERD) is generally considered among the most common etiologies of chronic cough. Indeed, cough management guidelines published by numerous respiratory societies worldwide recommend evaluation and treatment of GERD as an integral component of the diagnostic/therapeutic algorithm for the management of chronic cough. However, a significant number of patients with chronic cough presumed due to GERD do not report improvement despite aggressive acid-suppressive therapy. Some of these refractory cases may be due to the recently appreciated entity of non-acid or weakly acidic reflux. Further contributing to the controversy are recent studies demonstrating that patients with chronic cough do not have excessive reflux events relative to healthy volunteers. Although a temporal relationship between cough and reflux events has been suggested by studies utilizing impedance-pH monitoring of reflux events and objective cough recording, consensus is lacking in terms of whether this temporal relationship proves a causal link between reflux and cough. The 4th American Cough Conference, held in New York in June, 2013, provided an ideal forum for the debate of this issue between two internationally recognized experts in the field of reflux and chronic cough.

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Section: Jaclyn a Smith Against The Motionmentioning

confidence: 99%

A Causal Relationship Between Cough and Gastroesophageal Reflux Disease (GERD) has been Established: A Pro/Con Debate

Kahrilas

Smith

Dicpinigaitis

2013

Lung

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“…Strate et al [14] report in their randomized study that the Toupet procedure is more effective in reflux control than in the Nissen procedure. Others support our view, that all partial wraps have a higher recurrence rate for GERD, especially in dysmotility patients [25,26,27]. …”

Section: Discussionmentioning

confidence: 57%

Effect of Laparoscopic Antireflux Surgery on Esophageal Motility

Fuchs

Gutschow²,

Brinkmann³

et al. 2014

Dig Surg

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Background/Aims: The effect of laparoscopic antireflux surgery on esophageal motility is incompletely understood, and any indication for this procedure in patients with motility disorder is disputed in literature. We evaluated the influence of laparoscopic Nissen fundoplication on impaired esophageal motility. Methods: In this pathological manometric study, we divided the patients into two groups preoperatively: the hypomotility group (mean amplitude of esophageal contraction wave <40 mm Hg; HYPO group, n = 11) and the normal group (mean amplitude of esophageal contraction wave >40 mm Hg; NORM group, n = 43). The amplitudes of esophageal contraction waves 3 and 8 cm above the lower esophageal sphincter and the percentage of peristaltic contraction waves of the tubular esophagus were analyzed pre- and postoperatively. Results: In total, 54 patients with GERD underwent esophageal manometry before and 6 months after Nissen fundoplication. The length and pressure of the lower esophageal sphincter were increased in both groups postoperatively (p < 0.01). Patients in the HYPO group (n = 11) showed a statistically significant increase of mean amplitude of esophageal contraction (32.8 vs. 57.3 mm Hg; p < 0.01), while no change was found in the NORM group (n = 43). A total of 72% of patients with preoperative motility disorder showed normal postoperative manometry. Conclusion: Nissen fundoplication normalizes esophageal motility, especially in patients with preoperative hypomotility. Patients with impaired esophageal motility should not per se be excluded from antireflux surgery.

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“…Istotna poprawa nastąpiła szczegól-nie w 4 domenach: funkcjonowanie fizyczne, ból i dyskomfort, ograniczenia zwią zane z zaburzeniami zdrowia fizycznego i witalność [25]. Koch et al w swoim badaniu przedstawili ponadto wpływ chirurgicznego leczenia antyrefluksowego na poziom jakości życia chorych [26]. Do badania zakwalifikowano 100 pacjentów poddanych operacji antyrefluksowej (50 metodą Nissena, 50 metodą Toupeta).…”

Section: Operacyjne Leczenie Antyrefluksoweunclassified

“…Jakość życia chorych po zastosowaniu leczenia chirurgicznego zarówno metodą Nissena, jak i metodą Toupeta była znacząco lepsza od poziomu jakości życia chorych przed operacją. Pacjenci po operacji antyrefluksowej podkreślali występo-wanie zmniejszonej liczby objawów towarzyszą-cych chorobie, co w dużym stopniu wpłynęło na poprawę ich jakości życia [26]. Dodatkowo w kolejnym badaniu Koch et al ocenili wpływ chirurgicznego leczenia antyrefluksowego na poziom jakości życia chorych wśród 125 zakwalifikowanych do badania osób w okresie przed i rok po przebytej operacji [27].…”

Section: Operacyjne Leczenie Antyrefluksoweunclassified

The Impact of Clinical Symptoms and the Type of Treatment on Quality of Life in Patients with Gastroesophageal Reflux Disease – Review of the Literature

Bąk¹,

Dyrla²,

Gil³

2015

Piel. Zdr. Publ.

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A -koncepcja i projekt badania; B -gromadzenie i/lub zestawianie danych; C -analiza i interpretacja danych; D -napisanie artykułu; E -krytyczne zrecenzowanie artykułu; F -zatwierdzenie ostatecznej wersji artykułu StreszczenieChoroba refluksowa przełyku jako schorzenie przewlekłe stanowi poważny problem zarówno dla pacjentów, jak i ich najbliższego otoczenia. Prowadzi do obniżenia jakości życia, co w rezultacie może być przyczyną negatywnych zachowań i emocji. Jednym z podstawowych elementów opieki medycznej sprawowanej nad przewlekle chorym jest zapewnienie optymalnej jakości życia. Ocena jakości życia pacjenta mającego chorobę refluksową przełyku, a także rozpoznanie czynników wpływających na jakość życia takiej osoby pozwalają lepiej zrozumieć, jak schorzenie wpływa na codzienne funkcjonowanie. Występowanie objawów choroby refluksowej oraz rodzaj stosowanego leczenia znacząco wpływają na poziom jakości życia chorych. Dzięki skutecznemu leczeniu zmniejszają się bądź całkowicie ustępują objawy choroby, poprawia się więc jakość życia chorego. Dzięki opanowaniu ciężkości i czę-stości objawów, odpowiednio dobranemu leczeniu pacjenci mający chorobę refluksową przełyku mogą normalnie funkcjonować w życiu codziennym, a ich poziom jakości życia nieznacznie odbiega od jakości życia osób zdrowych (Piel. Zdr. Publ. 2015, 5, 3, 441-448).Słowa kluczowe: choroba refluksowa przełyku, jakość życia, zgaga, inhibitory pompy protonowej. AbstractGastroesophageal reflux disease is one of the most common gastrointestinal disorders. This chronic disease is a serious problem not only for patients but also for their immediate environment, because it leads to disability of the patient, may be the cause of negative behaviors and emotions, in effect reducing quality of life. Effective treatment of GERD is necessary to provide symptomatic relief and, in turn, to improve the patient's health-related quality of life. Symptoms of gastroesophageal reflux disease and the type of treatment have a substantial impact on health-related quality of life in patients with GERD. Thanks to controlling the symptoms and a proper type of treatment, people with GERD can lead normal lives and their quality of life is similar to quality of life in the general population (Piel. Zdr. Publ. 2015, 5, 3, 441-448).

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Laparoscopic Nissen versus Toupet fundoplication: objective and subjective results of a prospective randomized trial

Abstract: Both procedures equally improve quality of life and GERD symptoms. Bowel symptoms may increase after both procedures at the 3-month follow-up. Manometry and MII data favor Nissen fundoplication, but dysphagia and the inability to belch are more common compared to Toupet fundoplication.

Cited by 46 publications

References 34 publications

A Causal Relationship Between Cough and Gastroesophageal Reflux Disease (GERD) has been Established: A Pro/Con Debate

A Causal Relationship Between Cough and Gastroesophageal Reflux Disease (GERD) has been Established: A Pro/Con Debate

Effect of Laparoscopic Antireflux Surgery on Esophageal Motility

The Impact of Clinical Symptoms and the Type of Treatment on Quality of Life in Patients with Gastroesophageal Reflux Disease – Review of the Literature

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