Laparoscopic ovarian transposition for pelvic malignancies: indications and functional outcomes

Morice, Philippe; Castaigne, Damienne; Haie-Méder, Christine; Pautier, Patricia; Hassan, Janah El; Duvillard, P.; Gerbaulet, A.; Michel, G

doi:10.1016/s0015-0282(98)00284-2

Cited by 101 publications

(58 citation statements)

References 11 publications

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“…Through this outpatient surgical procedure, the ovaries are suspended above the pelvis and removed from the field of radiation. The risk of ovarian damage is reduced, although not entirely eliminated, as there can be extension of the radiation beyond the pelvis [30]. The use of GnRH agonists to downregulate the HPG axis prior to and during chemotherapy remains controversial, as conflicting results regarding their true protective effects have been reported [31,32].…”

Section: Barriers To Treatment and Referralmentioning

confidence: 99%

Results from the survey for preservation of adolescent reproduction (SPARE) study: gender disparity in delivery of fertility preservation message to adolescents with cancer

Köhler

Kondapalli

Shah

et al. 2010

J Assist Reprod Genet

172

135

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Purpose Diminished reproductive capacity is a devastating consequence of life-sparing therapies for childhood malignancy. In 2006, the American Society of Clinical Oncology (ASCO) published fertility preservation recommendations (ASCOR) emphasizing the importance of early discussion and intervention for fertility preservation strategies. Using the Survey for Preservation of Adolescent REproduction (SPARE), we sought to determine fertility preservation attitudes and practice patterns post-ASCOR from pediatric oncology specialists nationwide. Materials and methods The SPARE survey consists of 22 questions assessing pediatric oncology specialists' attitudes and practice patterns toward fertility preservation. Broad perspectives on fertility preservation, including a willingness to discuss fertility, knowledge of current fertility preservation methods and awareness of ASCOR, were assessed. Genet (2011) 28:269-277 DOI 10.1007 Capsule The SPARE survey captured marked disparities between pediatric oncologists' attitudes and practice patterns regarding fertility preservation for male and female pediatric oncology patients. Statement of Financial SupportResults The majority of respondents acknowledged that fertility threats are a major concern for them and agreed that all pubertal cancer patients should be offered a fertility consultation, but only 46% reported they refer male pubertal cancer patients to a fertility specialist prior to cancer treatment >50% of the time, and only 12% reported they refer female pubertal cancer patients to a fertility specialist prior to cancer treatment > 50% of the time. While 44% of respondents were familiar with the 2006 ASCOR, only 39% of those utilized them to guide decision-making in greater than half of their patients. Conclusion Our study demonstrates pediatric oncologists' motivation to preserve fertility in pediatric cancer patients; however, barriers to both gamete cryopreservation and referral to fertility specialists persist. Female pubertal patients are referred to fertility preservation specialists with much less frequency than are male pubertal patients, highlighting a disparity.

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Section: Barriers To Treatment and Referralmentioning

confidence: 99%

Results from the survey for preservation of adolescent reproduction (SPARE) study: gender disparity in delivery of fertility preservation message to adolescents with cancer

Köhler

Kondapalli

Shah

et al. 2010

J Assist Reprod Genet

172

135

View full text Add to dashboard Cite

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“…Morice et al [15] studied bilateral laparoscopic ovarian transposition in patients undergoing irradiation for pelvic tumors: One of these patients had been converted to laparotomy during laparoscopic oophoropexy and also received both brachytherapy and external beam radiation, which may have increased her risk of gonadotoxicity and she experienced ovarian failure. Hart et al [16] reported on an 18-year-old girl with medulloblastoma who underwent two laparoscopic surgeries to achieve oophoropexy to the Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Anterior ovarian transposition to the lower anterior abdominal wall has been described in a case report of a patient requiring radiotherapy to the craniospinal axis for a medulloblastoma [24]. The most common sites for lateral ovarian transposition are the paracolic gutters just above the pelvic brim and posterolateral to the uterus [15].…”

Section: Discussionmentioning

confidence: 99%

Needle oophoropexy: a new simple technique for ovarian transposition prior to pelvic irradiation

2011

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“…As taxas de sucesso na preservação da função dos ovários parecem estar relacionadas basicamente a dois fatores: a realização de radioterapia pós-operatória e a idade das pacientes. Desse modo, tem-se preconizado a preservação dos ovários em pacientes com menos de 40 anos 7 .…”

Section: Discussionunclassified

Preservação dos ovários em cirurgia radical para câncer do colo uterino

Vieira¹,

Silva²,

Vale³

et al. 2002

Rev. Bras. Ginecol. Obstet.

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mL). Das nove pacientes com níveis elevados de FSH, cinco (55,6%) haviam sido submetidas a radioterapia pós-operatória (p<0,0001). Não houve associação entre a idade das pacientes e os níveis de FSH (p=0,33). Cistos ovarianos funcionais ocorreram em quatro pacientes (7,7%Introdução O câncer do colo uterino é sério problema de saúde pública na América Latina, sendo a primeira causa de morte na população feminina em idade reprodutiva 1 . O tratamento de escolha para casos de câncer do colo uterino invasivo em estágios iniciais é a histerectomia radical com salpingooforectomia bilateral. Entretanto, a preservação dos ovários em pacientes jovens submetidas à cirurgia radical para câncer do colo uterino apresenta manutenção da função ovariana entre 70 e 83% dos casos, bem como baixa morbidade associada 2-4 . Tendo em vista que parcela significativa dos casos de câncer do colo uterino ocorre em mulheres jovens, a preservação dos ovários deve sempre ser oferecida à paciente, visto que a ooforectomia bilateral implicará sintomatologia vasomotora e gênito-urinária associada ao climatério e complicações mórbidas como a osteoporose. Além disso, a reposição estrogênica nas pacientes submetidas a ooforectomia implica comprometimento importante do orçamento familiar, devido ao baixo nível socioeconômico da maioria das pacientes com câncer do colo uterino 5,6 .Este estudo tem como objetivo a avaliação da função ovariana em pacientes com câncer do colo uterino, que se submeteram a histerectomia radical com manutenção dos ovários.

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Laparoscopic ovarian transposition for pelvic malignancies: indications and functional outcomes

Cited by 101 publications

References 11 publications

Results from the survey for preservation of adolescent reproduction (SPARE) study: gender disparity in delivery of fertility preservation message to adolescents with cancer

Results from the survey for preservation of adolescent reproduction (SPARE) study: gender disparity in delivery of fertility preservation message to adolescents with cancer

Needle oophoropexy: a new simple technique for ovarian transposition prior to pelvic irradiation

Preservação dos ovários em cirurgia radical para câncer do colo uterino

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