Laparoscopic ovarian transposition prior to pelvic radiation in young women with anorectal malignancies: a systematic review and meta‐analysis of prevalence

Tessier, Léa; McKechnie, Tyler; Lee, Yung; Park, Lily; Gangam, Nirupa; Eskicioglu, Cagla

doi:10.1111/codi.16571

Cited by 5 publications

(1 citation statement)

References 80 publications

(159 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Fertility-sparing strategies related to radiotherapy concern the preservation of the ovaries from pelvic irradiation by surgically removing them from the irradiation field before starting the radiotherapy cycles. Laparoscopic ovarian transposition before pelvic radiation in young women is widely described in the literature and affects girls affected not only by malignancies of genital origin but also tumors of the gastrointestinal tract and pelvic soft tissue malignancies [24]. In the present case, a toxic chemotherapy treatment was also expected, so it was very important to plan the removal of ovarian tissue for cryopreservation at the same time as the ovarian transposition [25].…”

Section: Discussionmentioning

confidence: 80%

Large Pelvic Mass in a Female Adolescent: Atypical Presentation and Successful Treatment of Extraskeletal Ewing Sarcoma

Perelli

Vizzielli

Cavaliere³

et al. 2023

Healthcare

View full text Add to dashboard Cite

Extraskeletal Ewing sarcoma is a rare soft tissue tumor primarily affecting pediatric patients. The treatment is currently based on a multidisciplinary approach which allows, in cases of localized disease, good survival rates. We report the case of a 15-year-old female patient with a rapidly growing suspected pelvic mass misdiagnosed following the preliminary radiological exams, which assessed the findings as a mass of ovarian origin. The girl underwent surgery and, thanks to histopathological, immunohistochemical and real-time polymerase chain reaction (RT-PCR) examinations, it was possible to make the right diagnosis and to administer the best treatment in terms of surgery, chemotherapy and radiotherapy, obtaining a long disease-free interval and no recurrence to date.

show abstract

Section: Discussionmentioning

confidence: 80%

Large Pelvic Mass in a Female Adolescent: Atypical Presentation and Successful Treatment of Extraskeletal Ewing Sarcoma

Perelli

Vizzielli

Cavaliere³

et al. 2023

Healthcare

View full text Add to dashboard Cite

show abstract

Fertility in young-onset colorectal patients with cancer: a review

Jiang,

Hua

2024

The Oncologist

View full text Add to dashboard Cite

Although the overall incidence and mortality of colorectal cancer have declined, diagnosed cases of young-onset colorectal cancer have increased significantly. Concerns about future fertility are second only to concerns about survival and may significantly affect the quality of life of young cancer survivors. Fertility preservation is an important issue in young-onset colorectal patients with cancer undergoing oncotherapy. Here, we discussed the effects of different treatments on fertility, common options for fertility preservation, factors affecting fertility preservation and improvement measures, and the relationship between fertility and pregnancy outcomes in young-onset colorectal patients with cancer.

show abstract

Uterine transposition for fertility preservation in pelvic cancers

Ribeiro,

Baiocchi,

Obermair

et al. 2024

Int J Gynecol Cancer

View full text Add to dashboard Cite

ObjectiveTo review rates of uterine preservation and gonadal function, surgical outcomes, and pregnancy outcomes in patients undergoing surgical uterine transposition.MethodsA structured search and analysis of the published literature on uterine transposition was conducted. Information on study type, sample size, patient characteristics, clinical indications, details of the surgical technique, trans-operative and post-operative results, success rates in preserving reproductive organ function and fertility were extracted.ResultsA total of 18 cases were reported to date. Patients’ median age was 29 (range 3–38) years. Rectal cancers accounted for 9 (50%) cases of published cases of uterine transposition, followed by 6 (33%) cervical squamous cell carcinomas, 1 (6%) vaginal squamous cell carcinoma, 1 (6%) sacral yolk sac tumor, and 1 (6%) pelvic liposarcoma. The median time for uterine transposition to the upper abdomen was 150 (range 80–360) min, and 90 (range 80–310) min for organ reimplantation in the pelvis. Cervical ischemia occurred in 5 (27.8%) cases, being the most commonly reported complication. The median follow-up time was 25 months, and three patients achieved spontaneous pregnancies resulting in successful gestations, out of five patients who were reported as having tried. One patient experienced recurrence and succumbed to the tumor during treatment.ConclusionsUterine transposition is a feasible and safe surgical approach that offers patients undergoing pelvic radiotherapy an option to preserve gonadal and uterine function, with the potential for spontaneous pregnancy.

show abstract

Laparoscopic ovarian transposition prior to pelvic radiation in young women with anorectal malignancies: a systematic review and meta‐analysis of prevalence

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 5 publications

References 80 publications

Large Pelvic Mass in a Female Adolescent: Atypical Presentation and Successful Treatment of Extraskeletal Ewing Sarcoma

Large Pelvic Mass in a Female Adolescent: Atypical Presentation and Successful Treatment of Extraskeletal Ewing Sarcoma

Fertility in young-onset colorectal patients with cancer: a review

Uterine transposition for fertility preservation in pelvic cancers

Contact Info

Product

Resources

About