Large B-Cell Lymphoma Occurring in a Breast Implant Capsule

Breast implant–associated anaplastic large cell lymphoma, a systematic review and in‐depth evaluation of the current understanding

“…Breast implants and breast implant capsules have been associated with several types of non ALCL cancers, including squamous cell carcinoma, large B cell lymphoma, primary T‐cell lymphoma, Sezary syndrome, and hairy cell leukemia . To add to this heterogeneity, ALK+ cases of lymphoma around a breast implant have also been documented despite the fact that BIA‐ALCL is nearly always ALK−, a feature now required for its diagnosis.…”

New B-cell Lymphomas in the Setting of a Previous Rare Breast Implant–Associated B-cell Lymphoma

“…3,4 Only 5 cases of implant-associated B-cell types have been reported in the literature, 2 including a previous case report about the patient described in this study published in Plastic and Reconstructive Surgery in 2014. 2 The majority of T-cell and B-cell breast implant–associated lymphomas are well localized, and implant removal alone has been reported in several cases as satisfactory treatment. 2 However, there is still no consensus on medical treatment as there are so few occurrences and limited long-term outcome studies.…”

“…1 Lymphomas associated with breast implants are even rarer and are mostly of the T-cell type. 2 These include approximately 60 reported cases of anaplastic large cell lymphoma associated with breast implants 2 and 4 cases of cutaneous T-cell lymphoma. 3,4 Only 5 cases of implant-associated B-cell types have been reported in the literature, 2 including a previous case report about the patient described in this study published in Plastic and Reconstructive Surgery in 2014.…”

“…2 These include approximately 60 reported cases of anaplastic large cell lymphoma associated with breast implants 2 and 4 cases of cutaneous T-cell lymphoma. 3,4 Only 5 cases of implant-associated B-cell types have been reported in the literature, 2 including a previous case report about the patient described in this study published in Plastic and Reconstructive Surgery in 2014. 2 The majority of T-cell and B-cell breast implant–associated lymphomas are well localized, and implant removal alone has been reported in several cases as satisfactory treatment.…”

“…2 The majority of T-cell and B-cell breast implant–associated lymphomas are well localized, and implant removal alone has been reported in several cases as satisfactory treatment. 2 However, there is still no consensus on medical treatment as there are so few occurrences and limited long-term outcome studies. In this report, we provide updates regarding the patient described previously in Plastic and Reconstructive Surgery , specifically the presentation of diffuse large B-cell lymphoma (DLBCL) involvement of the left breast and left leg 3 years after the initial diagnosis.…”