Large field of view, fast and low dose multimodal phase-contrast imaging at high x-ray energy

Astolfo, Alberto; Endrizzi, Marco; Vittoria, Fabio A.; Diémoz, Paul C.; Price, B.; Haig, Ian; Olivo, Alessandro

doi:10.1038/s41598-017-02412-w

Cited by 29 publications

(24 citation statements)

References 51 publications

(37 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several other XPCi imaging techniques exist, e.g., Talbot-Lau grating interferometry was used to investigate impact damage in composite plates [19]. However, EI offers several advantages in terms of practical implementation in fast, large field of view, and vibration-resistant industrial systems [20].…”

Section: Introductionmentioning

confidence: 99%

Enhanced composite plate impact damage detection and characterisation using X-Ray refraction and scattering contrast combined with ultrasonic imaging

Shoukroun

Massimi

Iacoviello

et al. 2020

Composites Part B: Engineering

View full text Add to dashboard Cite

Ultrasonic imaging and radiography are widely used in the aerospace industry for nondestructive evaluation of damage in fibre-reinforced composites. Novel phase-based Xray imaging methods use phase effects occurring in inhomogeneous specimens to extract additional information and achieve improved contrast. Edge Illumination employs a coded aperture system to extract refraction and scattering driven signals in addition to conventional absorption. Comparison with ultrasonic immersion C-scan imaging and with a commercial X-ray CT system for impact damage analysis in a small cross-ply carbon fibre-reinforced plate sample was performed to evaluate the potential of this new technique. The retrieved refraction and scattering signals provide complementary information, revealing previously unavailable insight on the damage 2 extent and scale, not observed in the conventional X-ray absorption and ultrasonic imaging, allowing improved damage characterisation.

show abstract

Section: Introductionmentioning

confidence: 99%

Enhanced composite plate impact damage detection and characterisation using X-Ray refraction and scattering contrast combined with ultrasonic imaging

Shoukroun

Massimi

Iacoviello

et al. 2020

Composites Part B: Engineering

View full text Add to dashboard Cite

show abstract

“…EI has proven its ability to work accurately with spatially and temporally incoherent x-ray sources (Munro et al 2012 ), reduced exposure times (Olivo et al 2011 ), higher x-ray energies, relatively flexible setup requirements and a large field of view (FOV) (Endrizzi et al 2015 , Zamir et al 2016 , Astolfo et al 2017 ). Following further development, EI would therefore be suitable for a series of applications, among which our focus here will be on a compact system for intra-operative specimen imaging.…”

Section: Introductionmentioning

confidence: 99%

A compact system for intraoperative specimen imaging based on edge illumination x-ray phase contrast

et al. 2019

Self Cite

View full text Add to dashboard Cite

A significant number of patients receiving breast-conserving surgery (BCS) for invasive carcinoma and ductal carcinoma in situ (DCIS) may need reoperation following tumor-positive margins from final histopathology tests. All current intraoperative margin assessment modalities have specific limitations. As a first step towards the development of a compact system for intraoperative specimen imaging based on edge illumination x-ray phase contrast, we prove that the system’s dimensions can be reduced without affecting imaging performance. We analysed the variation in noise and contrast to noise ratio (CNR) with decreasing system length using the edge illumination x-ray phase contrast imaging setup. Two-(planar) and three-(computed tomography (CT)) dimensional imaging acquisitions of custom phantoms and a breast tissue specimen were made. Dedicated phase retrieval algorithms were used to separate refraction and absorption signals. A ‘single-shot’ retrieval method was also used, to retrieve thickness map images, due to its simple acquisition procedure and reduced acquisition times. Experimental results were compared to numerical simulations where appropriate. The relative contribution of dark noise signal in integrating detectors is significant for low photon count statistics acquisitions. Under constant exposure factors and magnification, a more compact system provides an increase in CNR. Superior CNR results were obtained for refraction and thickness map images when compared to absorption images. Results indicate that the ‘single-shot’ acquisition method is preferable for a compact CT intraoperative specimen scanner; it allows for shorter acquisition times and its combination of the absorption and refraction signals ultimately leads to a higher contrast. The first CT images of a breast specimen acquired with the compact system provided promising results when compared to those of the longer length system.

show abstract

“…Such gratings are called line gratings in the following. In this context, different approaches have been published, for example an edge illumination scanning system 49 and Talbot-Lau imaging scanning systems 50 , 51 which show promising results. In a scanning setup object and gratings are moved relatively to each other (see Fig.…”

Section: Introductionmentioning

confidence: 99%

“… 51 scanned objects with a scanning velocity of 5 mm/s, Astolfo et al . 49 used a scanning velocity of 2.5 mm/s and Gromann et al . 50 of around 9 mm/s.…”

Section: Introductionmentioning

confidence: 99%

Talbot-Lau x-ray phase-contrast setup for fast scanning of large samples

Seifert

Ludwig

Kaeppler

et al. 2019

Sci Rep

View full text Add to dashboard Cite

Compared to conventional attenuation x-ray radiographic imaging, the x-ray Talbot-Lau technique provides further information about the scattering and the refractive properties of the object in the beam path. Hence, this additional information should improve the diagnostic process concerning medical applications and non-destructive testing. Nevertheless, until now, due to grating fabrication process, Talbot-Lau imaging suffers from small grating sizes (70 mm diameter). This leads to long acquisition times for imaging large objects. Stitching the gratings is one solution. Another one consists of scanning Talbot-Lau setups. In this publication, we present a compact and very fast scanning setup which enables imaging of large samples. With this setup a maximal scanning velocity of 71.7 mm/s is possible. A resolution of 4.1 lines/mm can be achieved. No complex alignment procedures are necessary while the field of view comprises 17.5 × 150 cm2. An improved reconstruction algorithm concerning the scanning approach, which increases robustness with respect to mechanical instabilities, has been developed and is presented. The resolution of the setup in dependence of the scanning velocity is evaluated. The setup imaging qualities are demonstrated using a human knee ex-vivo as an example for a high absorbing human sample.

show abstract

Large field of view, fast and low dose multimodal phase-contrast imaging at high x-ray energy

Cited by 29 publications

References 51 publications

Enhanced composite plate impact damage detection and characterisation using X-Ray refraction and scattering contrast combined with ultrasonic imaging

Enhanced composite plate impact damage detection and characterisation using X-Ray refraction and scattering contrast combined with ultrasonic imaging

A compact system for intraoperative specimen imaging based on edge illumination x-ray phase contrast

Talbot-Lau x-ray phase-contrast setup for fast scanning of large samples

Contact Info

Product

Resources

About