“…Thus detection of weak low frequency magnetic fields is crucial. 1,2) There are numerous low-field magnetic sensors that have been investigated for use in biosensors including coil-based sensors, 3,4) direct-current superconducting quantum interference devices (dc SQUIDs), 2,5,6) fluxgate magnetometers, [7][8][9] giant magneto-impedance sensors, [10][11][12] Hall effect sensors [13][14][15] and recently frequency-based sensors, [16][17][18] and magnetoresistive (MR)-based sensors. 1,[19][20][21][22] Above all others, MR-based sensors offer significant advantages: (i) MR sensors have an inherent advantage in size and power when compared to coil-based, fluxgate, and more complicated low-field sensing techniques such as SQUID and spin resonance magnetometers; 19) (ii) the technique used for fabricating MR sensors is a well-established technology for information storage which is CMOS compatible, large-scale, and cost-effective to produce; (iii) MR sensors also provide high sensitivity, adjustable detected field range, and room temperature (RT) operation.…”