Large oral focal mucinosis: a case report

Silva, Karla Rovaris da; Monteiro, Bárbara Vanessa de Brito; Norões, Thayse Silva Aragão; Godoy, Gustavo Pina; Miguel, Márcia Cristina da Costa

doi:10.1590/s1676-24442014000100007

Cited by 9 publications

(19 citation statements)

References 5 publications

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“…OFM stains positive with alcian blue, indicating the abundant mucins scattered around the connective tissue (3,10,15,17). Its treatment involves complete surgical excision, and no recurrence is reported (10,16,18). In the present case report, the excisional biopsy was performed.…”

Section: Discussionmentioning

confidence: 65%

A Case of Oral Focal Mucinosis

Nafarzadeh

Kiani

Emampanahi

et al. 2019

Zahedan J Res Med Sci

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Introduction:Oral focal mucinosis (OFM) is an uncommon soft tissue lesion of unknown etiology. It is presented as a harmless swelling that can be sessile or pedunculated. Histologically, OFM is characterized by focal myxoid degeneration of the connective tissue. The diagnosis of the lesion is established based on the histopathological analysis. OFM is treated with surgical excision and its recurrence is unreported. Case Presentation: In the present case report, a 53-year-old female presented with a lesion on the gingiva around the dental area of 44 and 45 that was clinically similar to irritation fibroma. An excisional biopsy was performed and the diagnosis was OFM based on the clinical and pathological findings. Conclusions: This case report emphasizes that it is nearly impossible to predict the detection of OFM. Therefore, although OFM is a rare lesion, it should be distinguished from other similar soft tissue lesions in the oral cavity.

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Section: Discussionmentioning

confidence: 65%

A Case of Oral Focal Mucinosis

Nafarzadeh

Kiani

Emampanahi

et al. 2019

Zahedan J Res Med Sci

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“…In the reviewed articles, no changes in bony tissues had been reported, except for a bone displacement case [6] and a case of cervical resorption of the dental root adjacent to the lesion [18]. Excessive production of hyaluronic acid and reduced production of collagen are two important etiologies of OFM.…”

Section: Discussionmentioning

confidence: 99%

“…Clinically, this lesion appears as an asymptomatic, exophytic, sessile or pedunculated lesion containing a mucoid myxomatous substance surrounded by a relatively dense collagenous connective tissue [1,2]. The lesion is often similar to the normal oral mucosa in color [2] and is typically 1 cm or less in diameter [6]. The lesion appears to develop more frequently in the mucosa covering bony areas [4,7].…”

Section: Introductionmentioning

confidence: 99%

“…Other involved oral sites are the buccal mucosa, tongue, and lips (both cutaneous and mucosal areas) [8,9]. OFM occurs during the fourth and fifth decades of life, predominantly in women (two females per male) [6,10]; it has been reported rarely in younger people [8,11]. Diagnosis should be made after the rejection of a number of benign lesions, including gingival hyperplasia, myxoma, fibroma, mucocele, pyogenic granuloma, peripheral giant cell granuloma (PGCG), peripheral ossifying fibroma, and epulis [5,12].…”

Section: Introductionmentioning

confidence: 99%

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Oral Focal Mucinosis: A Case Report and Literature Review

Agha‐Hosseini¹,

Sadrzadeh-Afshar

2018

J Islam Dent Assoc Iran

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Introduction: Oral focal mucinosis (OFM) is the soft tissue counterpart of cutaneous focal mucinosis (CFM) and is often misdiagnosed as an oral myxoma. OFM occurs during the fourth and fifth decades of life, predominantly in women (two females per male). Case Report: A 22-year-old lactating female presented with a growing painless, sessile tumor with pale pink color and a lobulated surface with ulcers at the depths of interlobular fissures in the premolar-molar area of the left mandibular alveolar ridge, dating back one year. The tumor was completely excised. No recurrence was observed during the follow-ups over the next three years. Conclusion: The current case appears to be the only one with an OFM reported during the breastfeeding period; therefore, the role of hormonal factors in the pathogenesis of the lesion should be taken into consideration.

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“…The myxoid tissue consist of an area of loose connective tissue formed by an accumulation of hyaluronic acid and widely spaced collagen fibers interspersed with stellate-shaped fibroblasts, with or without inflammation. [ 5 ] As similar features may be appreciated in odontogenic myxoma (OM) and nerve sheath myxoma, these lesions should be included in histological differential diagnosis of OFM. [ 6 ] OM is a true neoplasm of mesenchymal origin.…”

Section: Discussionmentioning

confidence: 99%

Oral focal mucinosis of posterior maxilla

Kumar

Kothi²,

Patil

et al. 2017

J Oral Maxillofac Pathol

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Oral focal mucinosis (OFM) is a rare connective tissue disorder characterized by myxoid degeneration of submucosal connective tissue. It usually presents as gingival or mucosal overgrowth. Due to its uncommon occurrence and lack of pathognomonic clinical or radiological features, diagnosis mainly relies on histopathological evaluation. The paper reports a rare case of large OFM in a 58-year-old female patient involving the posterior maxilla and hard palate. Diagnosis of the lesion was established based on histopathological and immunohistochemical analysis. The lesion was excised surgically and showed no recurrence at 1 year follow-up. The cases presented intend to bring OFM to the attention of oral pathologists and clinicians while considering the differential diagnosis of myxoid lesions of oral cavity.

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Large oral focal mucinosis: a case report

Cited by 9 publications

References 5 publications

A Case of Oral Focal Mucinosis

A Case of Oral Focal Mucinosis

Oral Focal Mucinosis: A Case Report and Literature Review

Oral focal mucinosis of posterior maxilla

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