Abstract-To solve the low-frequency breakdown inherent from the electric field integral equation (EFIE), an alternative new form of the EFIE is proposed by using the Coulomb-gauge Green's function of quasi-static approximation. Different from the commonly adopted Lorentz-gauge EFIE, the Coulomb-gauge EFIE separates the solenoidal and irrotational surface currents explicitly, which captures inductive and capacitive responses through electrodynamic and electrostatic Green's functions, respectively.By applying existing techniques such as the loop-tree decomposition, frequency normalization, and basis rearrangement, the Coulomb-gauge EFIE also can remedy the low-frequency breakdown problem. Through comparative studies between the Lorentz-gauge and Coulomb-gauge EFIE approaches from mathematical, physical and numerical aspects, the Coulomb-gauge EFIE approach shows the capability of solving low-frequency problems and achieves almost the same accuracy and computational costs compared to the Lorentz-gauge counterpart.