With the development of renewable energy, DC distribution power system (DPS) becomes more and more attractive. The stability of whole system is still a big concern though every single converter is well-designed based on the stand alone operation with sufficient stability. Since the cascaded connection of power converters is one of the most dominant connection forms in the DC DPS, the stability analysis of the cascaded system is very important to ensure stability of the whole system. Based on Lyapunov linearization method and Brayton-Moser's mixed potential theory, stability of equilibrium point and an estimation of the region of attraction are investigated for cascaded system in the DC DPS. Based on the analysis, stability prediction criteria for cascaded system under small-signal and large-signal disturbance are obtained. The two criteria is simple and straightforward, which can be unified to get a general stability criterion to predict system's stability under both small-signal and large-signal transient disturbance. The relationship between system parameters and the stability is presented and discussed in the paper. Therefore, instead of trial and error, the proposed criterion can predict and guarantee the stability operation of cascaded system during the design process, and it is also helpful to select matched power converters in system level design. The simulation and experimental results verify the effectiveness of the proposed criterion.