Laryngeal schwannoma as an acute airway presentation

Markou, Konstantinos; Dova, Stamatia; Poulios, Christos; Karkos, Petros D.

doi:10.1136/bcr-2016-214682

Cited by 6 publications

(12 citation statements)

References 15 publications

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“…Most commonly, the nerve of origin is the inner branch of the superior laryngeal nerve or small nerve fibers that innervate laryngeal submucosa. In 80% of cases, laryngeal schwannomas are located at the aryepiglottic fold, while 20% occur at the vocal or ventricular fold, as in our case 5 . Clinical manifestations of laryngeal schwannomas depend on its size and localization.…”

Section: Discussionsupporting

confidence: 53%

“…It is important to differentiate schwannoma from neurofibroma, because the latter have a higher incidence of malignant transformation (around 10% of cases) and a higher recurrence rate 1 . Presence of neurofibroma could also indicate possible neurofibromatosis 5 .…”

Section: Discussionmentioning

confidence: 99%

“…Schwannoma is a benign slow-growing encapsulated neurogenic tumor, originating from Schwann cells that surround somatic and autonomic peripheral and cranial nerves, except the olfactory and optic nerves which lack Schwann cell sheath 1,5,7 . Between 25% and 45% of all schwannomas are located in the head and neck area, predominantly in the parapharyngeal space 1 .…”

Section: Introductionmentioning

confidence: 99%

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Laryngeal schwannoma: A case report with short literature review

et al. 2021

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Introduction. Laryngeal schwannomas are rare benign neurogenic tumors. They are usually localized in the supraglottic portion of the larynx.Case report. We report a rare case of laryngeal schwannoma with a focus on clinical presentation, diagnosis and management. A 61-year old male patient with a 3-year history of hoarseness underwent telescopic examination which revealed an oval submucosal tumefaction of the left ventricular fold extending over the left vocal fold toward the right ventricular fold. Multi-slice computed tomography showed a 22x15mm well defined, oval heterodense mass in the region of the left ventricular fold, extending toward the left vocal fold and the posterior commissure of the larynx, with signs of initial compression lesion of the thyroid cartilage. Biopsy and histopathology report revealed a primary benign encapsulated mesenchymal tumor, while immunohistochemistry analysis confirmed schwannoma diagnosis. The patient underwent tracheotomy and left hemilaryngectomy, with complete removal of the tumor. There were no signs of recurrence at the six-month follow-up. Conclusion.Schwannomas are rare among benign tumors of the larynx and might grow for years before being diagnosed. Biopsy with histopathology analysis is used to confirm the diagnosis of laryngeal schwannoma, although extreme care should be taken during biopsy.Treatment consists of complete surgical excision, while surgical approach depends on the size and localization of the tumor, as well as on the presence of a peduncle.

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Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Laryngeal schwannoma: A case report with short literature review

et al. 2021

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“…Among the 479 articles resulting from our literature search, 60 primary research papers fulfilled our criteria ( Figure 1 ), providing a total of 74 laryngeal schwannoma patients for combined analysis ( Table 1 and Supplemental Tables S1 and S2, available in the online version of the article). 2-61 The included studies consisted primarily of single case reports (n = 55), 4 reports of 2 cases, and 1 larger case series of 11 patients. The mean age at diagnosis was 43.4 years, with women presenting at a later age compared with men (47.3 years vs 32.8, P < .05).…”

Section: Resultsmentioning

confidence: 99%

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Tulli

Bondi

Smart

et al. 2017

Otolaryngol.--head neck surg.

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Objective This review summarizes the clinical features, diagnostic workup, and surgical treatment of laryngeal schwannoma with the aim of providing guidance for the management of this rare disease. The collated data allowed the statistical testing of several hypotheses, including the efficacy of endoscopic vs open surgical intervention and the usefulness of preoperative biopsy. Data Sources PubMed, Google Scholar, Cochrane, and SCOPUS. Review Methods Basic epidemiological and clinical presentation data were collated together with details of diagnostic image modality, lesion attributes, and the use of preoperative biopsy. Surgical approach to intervention and outcome was also collated and simple statistical analyses applied. Results The 60 original articles selected provided a combined cohort of 74 patients for review. The combined data revealed that schwannoma with pedunculated morphology were always safely removed by endoscopic resection regardless of size and should be treated as a separate entity. Of the nonpedunculated schwannoma, larger tumors were more likely to undergo an open approach, which in turn was associated with higher rates of tracheotomy and postoperative vocal fold paralysis. The small cohort did not reveal a significant association between surgery type and persistent disease. Interestingly, the data revealed a significant association between the use of incisional biopsy and persistent disease. Cases exhibiting extralaryngeal extension of the lesion were shown to exclusively belong to patients with neurofibromatosis/schwannomatosis syndromes. Conclusions Taken together, these findings suggest that incisional biopsy should be avoided, and given the benign nature of the pathology, the least invasive radical approach should be employed.

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“…It is a slow growing encapsulated tumor commonly presenting in the fourth and fifth decade of life, especially women. 2 The main symptoms are usually secondary to the mass effect like dysphagia, dysphonia, pharyngeal globus sensation and respiratory distress with inspiratory stridor. Here we report a supraglottic schwannoma with initial presentation of hoarseness of voice with no significant medical history except for personal habits of smoking and drinking.…”

mentioning

confidence: 99%

Schwannoma of False Vocal Cord - A Rare Entity

Deo¹,

Maharjan

Karna³

2021

Nep. J. Health Sci.

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Laryngeal Schwannoma is rare comprising 0.1 – 1.5% of all benign laryngeal tumors. The most common site in larynx is aryepiglottic fold followed by arytenoids, ventricular folds, and vocal cord. Patients present with the symptoms of hoarseness, dysphagia or globus sensation. We present a 33-year-old male with supraglottic schwannoma who experienced hoarseness of voice for three months. The patient underwent micro laryngeal surgery and submucosal solid tumor of false vocal cord was removed. Postoperative recovery was uneventful and after one month of follow up the patient was improving with no hoarseness of voice.

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Laryngeal schwannoma as an acute airway presentation

Cited by 6 publications

References 15 publications

Laryngeal schwannoma: A case report with short literature review

Laryngeal schwannoma: A case report with short literature review

Diagnosis and Treatment of Laryngeal Schwannoma: A Systematic Review

Schwannoma of False Vocal Cord - A Rare Entity

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