Laryngeal tuberculosis: CT findings.

Moon, Woo Kyung; Han, Mi-Young; Chang, Kyung Hee; Kim, H J; Im, Jung Gi; Yeon, Kyung Mo; Han, Man-Seung

doi:10.2214/ajr.166.2.8553964

Cited by 36 publications

(18 citation statements)

References 8 publications

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“…The response of laryngeal TB to antituberculous drugs is high [12]. In our patient, the symptoms and signs almost completely disappeared in 1 month.…”

Section: Discussionsupporting

confidence: 49%

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Primary Tuberculosis Involving Epiglottis: A Rare Case Report

et al. 2009

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“…The response of laryngeal TB to antituberculous drugs is high [12]. In our patient, the symptoms and signs almost completely disappeared in 1 month.…”

Section: Discussionsupporting

confidence: 49%

“…In our patient, the symptoms and signs almost completely disappeared in 1 month. It is important to keep in mind that untreated laryngeal TB may lead to laryngeal stenosis and/or cricoarytenoid fixation [12].…”

Section: Discussionmentioning

confidence: 99%

Primary Tuberculosis Involving Epiglottis: A Rare Case Report

et al. 2009

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“…El compromiso nasal, nasosinusal, ótico, ocular, tiroideo, de garganta y de lengua es mucho menos frecuente (15)(16)(17)(18)(19).…”

Section: Discussionunclassified

Diagnóstico patológico y molecular de un caso de tuberculosis laríngea primaria en un médico

et al. 2013

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Contribución de los autores:Guillermo Campos: realización de los procedimientos quirúrgicos, revisión del manuscrito. Diana Palacios, Johanna Álvarez y Margarita Baldión: realización del estudio histopatológico, revisión y comentario del manuscrito. Leonardo Jurado: revisión de la historia clínica y la literatura científica pertinente, interpretación de los análisis moleculares microbiológicos y redacción del manuscrito. La tuberculosis laríngea primaria es una enfermedad rara con una amplia gama de manifestaciones clínicas. Se reporta el caso de un médico otorrinolaringólogo con diabetes de tipo II y con diagnóstico de tuberculosis laríngea primaria. El diagnóstico de cáncer de cuerda vocal se había considerado en otra institución, y al ingreso el paciente sólo presentaba disfonía de seis meses de evolución. En el estudio histopatológico se encontraron granulomas, células gigantes multinucleadas, fibrosis y necrosis, y en la tinción de Ziehl-Neelsen, bacilos ácido-alcohol resistentes. El cultivo del tejido de cuerda vocal para micobacterias y la PCR-IS6110 fueron positivos. La cepa de Mycobacterium tuberculosis demostró sensibilidad a todos los medicamentos de primera línea. Se inició tratamiento según la estrategia DOTS (Directly Observed Treatment, Short-course). Se discute la presentación clínica, los diagnósticos diferenciales, el abordaje diagnóstico y los factores de riesgo asociados y se hace una breve revisión de la literatura.Palabras clave: Mycobacterium tuberculosis, reacción en cadena de la polimerasa, tuberculosis laríngea, granuloma, disfonía. doi: http://dx.doi.org/10.7705/biomedica.v34i1.1624 Pathological and molecular diagnosis in a case of primary laryngeal tuberculosis in a physicianPrimary laryngeal tuberculosis is a rare disease with a wide variety of clinical manifestations. We report the case of an ear-nose and throat diabetic physician with primary laryngeal tuberculosis. The diagnosis of laryngeal cancer had been considered before in another institution, and at the patient's admission, he only presented dysphonia with a six-month evolution. The vocal cord histological examination showed granulomas, giant cells, fibrosis and necrosis, and the Ziehl-Neelsen staining showed acid-alcohol resistant bacilli. The culture from vocal cord tissue was positive for mycobacteria, and IS6110-PCR was positive too. The Mycobacterium tuberculosis strain was sensitive to first line drugs. Treatment using directly observed therapy short-course (DOTS) was initiated. Clinical presentation, differential diagnosis, diagnostic workup, associated risk factors and a brief literature revision are discussed in this article.

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“…In adults, the thickening of the basal membrane of the vocal cords was found to be related to benign lesions of the vocal cords, most often in response to vibratory effects 1,2 , infectious diseases such as tuberculosis 9 , accidents or surgeries 10 , and traumas from a variety of causes 9 . In our study, the thickening of the basal membrane of the vocal cords was found most frequently in subjects whose cause of death was of respiratory alteration, among which were infectious causes such as pneumonia and tuberculosis.…”

Section: Discussionmentioning

confidence: 99%

“…However, more recent studies have shown that this lesion is not related to sudden infant death syndrome 8 and that it is the most commonly found lesion in autopsies of children below 1 year of age who have died for a variety of reasons 7 . In adults, the thickening of the basal membrane of the vocal cords has been found to be related to benign lesions of the vocal cords, most often as a response to vibrating effects 1,2 , infectious diseases such as tuberculosis 9 , and accidents or surgeries 10 . The purpose of this study is to identify the possible morphological alterations of the basal membrane of the vocal cords and thus to attempt to identify an association between these alterations and the cause of death of autopsied adults.…”

mentioning

confidence: 99%

Relationship between the morphologic alterations of vocal cords from adult autopsies and the cause of death

et al. 2004

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PURPOSE:The purpose of this study was to identify the possible alteration in the thickness of the epithelium basal membrane of the vocal cords and correlate it with the cause of death.METHOD: Larynxes collected from adult autopsies during the period of 1993 to 2001 were utilized. We used the hematoxylin-eosin and periodic acid-Schiff staining methods for the morphological and morphometric analysis.RESULTS: Sixty-six vocal cords were analysed; increased thickness was identified in 14 cases (21.2%), with equal proportions between the genders. Increased vocal-cord thickness was more frequent in patients of the white ethnicity (12 cases, 85.7%). Respiratory alterations were found in 10 (71.4%) of the cases with increased vocal-cord thickness. Of the patients that were maintained with mechanical ventilation before death, 7 (18.4%) had thickening of the basal membrane. Among the smokers, 9 (19.63%) had basal membrane thickening.CONCLUSION: No statistically significant differences were found between the cases in which the cause of death was related to respiratory diseases as compared to non-respiratory diseases and the thickening of the basal membrane of the vocal cords. However, new studies are needed in order to verify the etiopathogenesis of this thickening.

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Laryngeal tuberculosis: CT findings.

Cited by 36 publications

References 8 publications

Primary Tuberculosis Involving Epiglottis: A Rare Case Report

Primary Tuberculosis Involving Epiglottis: A Rare Case Report

Diagnóstico patológico y molecular de un caso de tuberculosis laríngea primaria en un médico

Relationship between the morphologic alterations of vocal cords from adult autopsies and the cause of death

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