Laser-assisted surface processing for functionalization of polymers on micro- and nano-scale

Rakebrandt, J.-H.; Zheng, Yijing; Besser, Heino; Scharnweber, Tim; Seifert, Hans Jürgen; Pfleging, Wilhelm

doi:10.1007/s00542-019-04633-7

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…In order to compare four different parameters of the LIPSS manufacturing process, four quadrants were created in each sample with a femtosecond laser (Tangerine, Amplitude Systèmes, France) built in a micromachining system PS450-TO (Optec s.a., Belgium). Like a cross, separating the four quadrants, the substrate material can serve as a basis for comparison between the polished and the textured titanium for tests with fibroblasts (Figure 1) [25][26][27][28][29].…”

Section: Bme Frontiersmentioning

confidence: 99%

Laser-Treated Surfaces for VADs: From Inert Titanium to Potential Biofunctional Materials

et al. 2022

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Objective. Laser-treated surfaces for ventricular assist devices. Impact Statement. This work has scientific impact since it proposes a biofunctional surface created with laser processing in bioinert titanium. Introduction. Cardiovascular diseases are the world’s leading cause of death. An especially debilitating heart disease is congestive heart failure. Among the possible therapies, heart transplantation and mechanical circulatory assistance are the main treatments for its severe form at a more advanced stage. The development of biomaterials for ventricular assist devices is still being carried out. Although polished titanium is currently employed in several devices, its performance could be improved by enhancing the bioactivity of its surface. Methods. Aiming to improve the titanium without using coatings that can be detached, this work presents the formation of laser-induced periodic surface structures with a topology suitable for cell adhesion and neointimal tissue formation. The surface was modified by femtosecond laser ablation and cell adhesion was evaluated in vitro by using fibroblast cells. Results. The results indicate the formation of the desired topology, since the cells showed the appropriate adhesion compared to the control group. Scanning electron microscopy showed several positive characteristics in the cells shape and their surface distribution. The in vitro results obtained with different topologies point that the proposed LIPSS would provide enhanced cell adhesion and proliferation. Conclusion. The laser processes studied can create new interactions in biomaterials already known and improve the performance of biomaterials for use in ventricular assist devices.

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Section: Bme Frontiersmentioning

confidence: 99%

Laser-Treated Surfaces for VADs: From Inert Titanium to Potential Biofunctional Materials

et al. 2022

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“…Moreover, when the irradiation occurs in a low-pressure gas environment, such nanocrystal clusters can be deposited as a NPs-film coating on substrates [ 51 , 52 ]. By carefully adjusting the irradiation conditions (e.g., wavelength, fluence, repetition frequency), short-pulse lasers can serve as surface texturing tools to create varieties of micro- and nano-motives in view of tissue engineering applications [ 6 , 53 , 54 , 55 , 56 , 57 ]. In one single pulse, a short-pulsed laser can serve for high-resolution deposition and direct patterning with a variety of materials, including biological moiety without alteration issues to create a specific 3D microenvironment for bioprinting [ 58 , 59 ].…”

Section: Introductionmentioning

confidence: 99%

Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges

et al. 2021

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Driven by flexibility, precision, repeatability and eco-friendliness, laser-based technologies have attracted great interest to engineer or to analyze materials in various fields including energy, environment, biology and medicine. A major advantage of laser processing relies on the ability to directly structure matter at different scales and to prepare novel materials with unique physical and chemical properties. It is also a contact-free approach that makes it possible to work in inert or reactive liquid or gaseous environment. This leads today to a unique opportunity for designing, fabricating and even analyzing novel complex bio-systems. To illustrate this potential, in this paper, we gather our recent research on four types of laser-based methods relevant for nano-/micro-scale applications. First, we present and discuss pulsed laser ablation in liquid, exploited today for synthetizing ultraclean “bare” nanoparticles attractive for medicine and tissue engineering applications. Second, we discuss robust methods for rapid surface and bulk machining (subtractive manufacturing) at different scales by laser ablation. Among them, the microsphere-assisted laser surface engineering is detailed for its appropriateness to design structured substrates with hierarchically periodic patterns at nano-/micro-scale without chemical treatments. Third, we address the laser-induced forward transfer, a technology based on direct laser printing, to transfer and assemble a multitude of materials (additive structuring), including biological moiety without alteration of functionality. Finally, the fourth method is about chemical analysis: we present the potential of laser-induced breakdown spectroscopy, providing a unique tool for contact-free and space-resolved elemental analysis of organic materials. Overall, we present and discuss the prospect and complementarity of emerging reliable laser technologies, to address challenges in materials’ preparation relevant for the development of innovative multi-scale and multi-material platforms for bio-applications.

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Advances in laser-based surface texturing for developing antifouling surfaces: A comprehensive review

Cholkar,

McCann,

Perumal

et al. 2023

Applied Surface Science Advances

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Laser-assisted surface processing for functionalization of polymers on micro- and nano-scale

Cited by 4 publications

References 21 publications

Laser-Treated Surfaces for VADs: From Inert Titanium to Potential Biofunctional Materials

Laser-Treated Surfaces for VADs: From Inert Titanium to Potential Biofunctional Materials

Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges

Advances in laser-based surface texturing for developing antifouling surfaces: A comprehensive review

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