Laser-Induced Mesoporous Nickel Oxide as a Highly Sensitive Nonenzymatic Glucose Sensor

Abstract

In this paper, we present a novel laser-induced oxidation procedure for in situ formation of nickel oxide nanoporous structures directly onto the nickel surface as a highly sensitive nonenzymatic glucose sensor. The formation of mesoporous nickel oxide is confirmed by field-emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction. Electrochemical properties of the pristine and laser-induced oxidized nickel (LIO-Ni) films were studied using cyclic voltammetry and electrochemical impedance spectroscopy. The unique three-dimensional mesoporous architecture of the oxide film on the LIO-Ni electrode resulted in a dramatic enhancement in electrochemical reduction/oxidation performance with a 10-fold increase in electrocatalytic activity for nonenzymatic glucose oxidation as compared to the pristine-Ni electrode. The LIO-Ni biosensor performance was successfully examined for the amperometric detection of glucose over a wide concentration range from 5 μM to 1.1 mM with a high linear sensitivity of 5222 μA mM −1 cm −2 . The limit of detection was obtained as low as 3.31 μM with a signal-tonoise ratio of 3. Furthermore, the LIO-Ni electrode showed outstanding long-term stability, reproducibility, and high selectivity in the presence of various interfering agents including uric acid, L-ascorbic acid, acetaminophen, glutamic acid, and citric acid. The demonstrated laser-induced oxidation process can be potentially adapted to the scalable manufacturing of a wide range of other easyto-use and robust metal oxide-based sensors for nonenzymatic biosensing applications.

An amphiprotic paper-based electrode for glucose detection based on layered carbon nanotubes with silver and polystyrene particles

“…These results indicated that the redox reaction on the CNT-NH 2 -Ag/PS paper electrode was a diffusion-controlled electrochemical process. [62][63][64] whereas their mechanisms for glucose redox in neutral [66][67][68] and acidic solutions were not clear. [69][70][71] For the current CNT-NH 2 -Ag/PS paper electrode, the redox reaction of glucose was performed in a neutral solution (Na 2 SO 4 system).…”

Laser‐induced phonon and magnon properties of NiO nanoparticles: A Raman study

“…NiO is a well‐known antiferromagnetic (AFM) material with high Néel temperature (523 K) and has large applications in the fields of memory devices, rechargeable batteries, gas sensors, and fuel cells. [ 1–7 ] Moreover, electrically insulating NiO thin films are widely used in spintronic devices for the enhancement of spin currents. [ 8,9 ] The AFM and spin behavior of NiO nanostructures depends on the parameters like particle size, morphology, structure, Ni vacancy concentration, and surface defects.…”

Solid‐State Fabrication of Cu2O/CuO Hydroxide Nanoelectrode Array onto Graphene Paper by Thermal Dewetting for High‐Sensitive Detection of Glucose

“…[ 21,22 ] Laser‐assisted dewetting at molten phase has been described in the literature. [ 23 ] The laser‐assisted process shows several advantages with respect to conventional physical and chemical processes, such as green, tunable fabrication in ambient condition and scalability. [ 24–27 ]…”