Lasers: Principles and Surgical Applications

Shokrollahi, Kayvan; Raymond, E Blackwell; Murison, Maxwell

doi:10.1016/s1743-9191(06)60023-x

Cited by 31 publications

(32 citation statements)

References 41 publications

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“…Birçok lazer sistemi birim alan ölçütü olarak cm 2 kullanır. Dolayısı ile enerji akımı güç veya enerji yoğunluğu olarak da adlandırılır 3,6,7 . Enerji Dansitesi (irradians=w/cm 2 ): Deride belli bir alana verilen güçtür 3 .…”

Section: Lazerde Temel Kavramlarunclassified

“…Lazer ışığı diğer ışıkların aksine aynı dalga boyunda ve monokromatik (sadece tek bir renkten oluşan) özelliktedir 3,6,9,10 . Lazer ışığının monokromatik özellikte olması lazer teknolojisinin klinik uygulamalarda kullanılmasında büyük öneme sahiptir çünkü kutanöz kromoforlar selektif olarak değişik dalga boylarında emilime uğrarlar 8 .…”

Section: Lazer Prensipleriunclassified

“…Q anahtarlı Nd:YAG lazer 1064 nm dalga boyunda infrared ışık yayıp siyah renkli tatuajların çıkarımında, Ota nevüs gibi bazı benin pigmente lezyonların tedavisinde etkin olarak kullanılmaktadır 4,6 . Dermiste 2-3 mm derinliğe penetre olabilmelerinden ötürü derin dermal pigmentasyon tedavisinde de yeri vardır 14 .…”

Section: Nd:yag Lazerunclassified

“…Dermiste 2-3 mm derinliğe penetre olabilmelerinden ötürü derin dermal pigmentasyon tedavisinde de yeri vardır 14 . Uzun atımlı modu istenmeyen kılların tedavisinde (epilasyon) kullanılabilir 6 .…”

Section: Nd:yag Lazerunclassified

“…Her ne kadar birçok sistem 755 nm dalga boyunda kırmızı ışık yaysa da, 701 ile 826 nm dalga boyu arasında ışık yayabilme özelliğine sahiptir 6,14 .…”

Section: Aleksandrite Lazerunclassified

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Lazere Giriş ve Genel Bilgiler

...

2012

Turkderm

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Section: Lazerde Temel Kavramlarunclassified

Section: Lazer Prensipleriunclassified

Section: Nd:yag Lazerunclassified

“…Her ne kadar birçok sistem 755 nm dalga boyunda kırmızı ışık yaysa da, 701 ile 826 nm dalga boyu arasında ışık yayabilme özelliğine sahiptir 6,14 .…”

Section: Aleksandrite Lazerunclassified

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Lazere Giriş ve Genel Bilgiler

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2012

Turkderm

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Ultrasonic modulation of tissue optical properties in ex vivo porcine skin to improve transmitted transdermal laser intensity

et al. 2017

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Assessment of a 3050/3200 nm fiber laser system for ablative fractional laser treatments in dermatology

et al. 2022

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Background and Objectives: Mid-infrared (IR) ablative fractional laser treatments are highly efficacious for improving the appearance of a variety of dermatological conditions such as photo-aged skin. However, articulated arms are necessary to transmit the mid-IR light to the skin, which restricts practicality and clinical use. Here, we have assessed and characterized a novel fiber laser-pumped difference frequency generation (DFG) system that generates ablative fractional lesions and compared it to clinically and commercially available thulium fiber, Erbium:YAG (Er:YAG), and CO 2 lasers. Materials and Methods: An investigational 20 W, 3050/3200 nm fiber laser pumped DFG system with a focused spot size of 91 µm was used to generate microscopic ablation arrays in ex vivo human skin. Several pulse energies (10-70 mJ) and pulse durations (2-14 ms) were applied and lesion dimensions were assessed histologically using nitro-blue tetrazolium chloride stain. Ablation depths and coagulative thermal damage zones were analyzed across three additional laser systems. Results: The investigational DFG system-generated deep (>2 mm depth) and narrow (<100 µm diameter) ablative lesions surrounded by thermal coagulative zones of at least 20 µm thickness compared to 13, 40, and 320 µm by the Er:YAG, CO 2 , and Thulium laser, respectively. Conclusion: The DFG system is a small footprint device that offers a flexible fiber delivery system for ablative fractional laser treatments, thereby overcoming the requirement of an articulated arm in current commercially available ablative lasers. The depth and width of the ablated microcolumns and the extent of surrounding coagulation can be controlled; this concept can be used to design new treatment procedures for specific indications. Clinical improvements and safety are not the subject of this study and need to be explored with in vivo clinical studies.

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Lasers: Principles and Surgical Applications

Cited by 31 publications

References 41 publications

Lazere Giriş ve Genel Bilgiler

Lazere Giriş ve Genel Bilgiler

Ultrasonic modulation of tissue optical properties in ex vivo porcine skin to improve transmitted transdermal laser intensity

Assessment of a 3050/3200 nm fiber laser system for ablative fractional laser treatments in dermatology

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