Late Intestinal Complications of Cystic Fibrosis

Intestinal Obstruction and Mucoviscidosis

“…The second obstruction was presumably caused only by the presence of a plug of inspissated mucoid material. Mullins et al (1965) objected to the use of the term meconium ileus equivalent on the basis th a t " it referred only to one aspect of the sym ptom atology" . The cases reported here emphasizes this point.…”

“…Increasing fam iliarity with this clinical picture will presum ably lead to more cases being treated by medical means. Indeed, there are several instances reported in the literature in which medical treatm ent was wholly successful (Halllterg, 1964: Mullins et al, 1965. A ttention m ust be drawn to the occurrence of an intus susception or even a volvulus which may not improve without surgical intervention.…”

“…As in the case reported here, the histological appearance of the gut in those instances in which it had been studied showed markedly distended mucous glands extending " stream ers" into a covering layer of adherent mucus. It is likely that this abnormally viscid mucus serves as the leading point for the intussusception (Hallberg, 1964: Jewett andAterman, 1964;Snyder et al, 1964;Mullins et al, 1965). …”

Cystic fibrosis

“…The term meconium ileus equivalent (MIE) is used to describe a syndrome of small intestinal obstruction seen in older children and adults with CF (Mullins, Talamo and di Sant'Agnese, 1965;Hunton, Long and Tsumagari, 1966). MIE can be an acute life-threatening complication.…”

Medium Chain Triglycerides in Paediatric Practice

“…Troublesome abdominal discomfort, distension, and pain related to gaseous distension and inspissation of intestinal contents occur not uncommonly in CF (Gracey, Burke, and Anderson, 1969b). Severe abdominal pain or even intestinal obstruction occurs (Mullins, Talamo, and di Sant'Agnese, 1965), and may be aggravated by abnormal bulk of intestinal contents. These symptoms are improved by using MCT (Gracey and Anderson, 1969).…”