Late-onset angioedema after interruption of angiotensin converting enzyme inhibitor therapy

Dyer, Philip D.

doi:10.1016/0091-6749(94)90391-3

Cited by 21 publications

(13 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous case reports have also implicated dental surgery, local anesthetics and interruption of ACEI therapy as possible triggers for angioedema but were not evaluated in this analysis and the pathophysiology was not been reported. [26][27][28][29][30][31] Additionally, to our knowledge, there are no data to suggest differences between ACEI themselves, such as whether one ACEI is a higher risk for causing angioedema compared to another ACEI. However, this is certainly possible and would need to be studied further.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of ACE Inhibitor Angioedema Utilizing a Large Electronic Health Record

Banerji

Blumenthal

Lai

et al. 2017

The Journal of Allergy and Clinical Immunology: In Practice

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Epidemiology of ACE Inhibitor Angioedema Utilizing a Large Electronic Health Record

Banerji

Blumenthal

Lai

et al. 2017

The Journal of Allergy and Clinical Immunology: In Practice

View full text Add to dashboard Cite

show abstract

“…29 Such a delayed presentation may represent sporadic cases of angioedema, idiopathic or otherwise uncategorized with no true temporal relationship to ACE inhibitor therapy. 29 Such a delayed presentation may represent sporadic cases of angioedema, idiopathic or otherwise uncategorized with no true temporal relationship to ACE inhibitor therapy.…”

Section: Incidence and Onsetmentioning

confidence: 99%

“…Cases of late-onset angioedema have also been reported at variable times after discontinuation of an ACE inhibitor. 29 Such a delayed presentation may represent sporadic cases of angioedema, idiopathic or otherwise uncategorized with no true temporal relationship to ACE inhibitor therapy. How long it takes to develop ACE inhibitor-related angioedema is an important consideration.…”

Section: Incidence and Onsetmentioning

confidence: 99%

Angioedema in Heart Failure: Occurrence With ACE Inhibitors and Safety of Angiotensin Receptor Blocker Therapy

Sica

Black

2002

Congestive Heart Failure

View full text Add to dashboard Cite

Angioedema is a well-known side effect of treatment with an angiotensin-converting enzyme (ACE) inhibitor and one that we have been willing to accept in view of the incidence of the problem and the clear benefits of this class of agents in numerous clinical situations. Angioedema is also seen with angiotensin receptor blocker (ARB) therapy but much less frequently than with ACE inhibitors. The mechanism for angioedema with ARB therapy remains poorly defined. ACE inhibitor-related angioedema occurs more commonly in black patients. The basis for an increased risk of angioedema in black patients remains unclear. Angioedema can be life-threatening but more times than not it can be managed with conservative treatment measures including specifically the discontinuation of the medication and/or administration of an antihistamine and/or epinephrine. Occasionally, maneuvers to protect the integrity of the airway may be needed. In a heart failure patient having previously experienced ACE inhibitor-related angioedema, ARBs should be used cautiously since angioedema has been reported with ARB therapy in heart failure patients. The need to reduce renin-angiotensin aldosterone system activity in a heart failure patient would seem to justify the small risk of angioedema with ARB therapy in a patient having previously experienced ACE inhibitor-related angioedema.

show abstract

“…Other less commonly affected areas include the cheeks, nose, uvula, extremities, genitalia, and viscera (7)(8)(9). Although angioedema usually develops within a week after starting an ACEI, there are cases of delayed angioedema occurring even after the ACE inhibitor has been discontinued (10). Angiotensin receptor blockers also have been shown to cause angioedema; therefore, it is recommended that this class of medications also be avoided in patients with ACEI-RA (11).…”

Section: Discussionmentioning

confidence: 96%

Penile Angioedema Developing After 3 Years of ACEI Therapy

Miller

Sweis

Toerne

2012

The Journal of Emergency Medicine

View full text Add to dashboard Cite

Late-onset angioedema after interruption of angiotensin converting enzyme inhibitor therapy

Cited by 21 publications

References 4 publications

Epidemiology of ACE Inhibitor Angioedema Utilizing a Large Electronic Health Record

Epidemiology of ACE Inhibitor Angioedema Utilizing a Large Electronic Health Record

Angioedema in Heart Failure: Occurrence With ACE Inhibitors and Safety of Angiotensin Receptor Blocker Therapy

Penile Angioedema Developing After 3 Years of ACEI Therapy

Contact Info

Product

Resources

About