Late-Onset Corynebacterium Endophthalmitis Following Laser Posterior Capsulotomy

Abstract

Abstract. Four months following uncomplicated cataract extraction, a patient underwent Nd: YAG laser posterior capsulotomy. Three days later, she presented with pain, hand motions vision, and severe anterior uveitis and vitritis. A coincident retinal detachment led to a delay in diagnosing the etiology of this intraocular inflammation. After recurrent episodes of inflammation that were initially responsive to corticosteroids, the patient underwent a vitrectomy, lens explantation, capsulectomy, and intravitreal antibiotic injections, which resulted in complete resolution of the intraocular inflammation with a best-corrected visual acuity of 20/60. Corynebacterium species was ultimately cultured from the capsular tissue. The release of sequestered bacterial organisms must be considered in the differential diagnosis of persistent or unusually intense inflammation following laser posterior capsulotomy. [Ophthalmic Surg Lasers Imaging 2004;35:159-161.]

Susceptibility comparisons of normal preoperative conjunctival bacteria to fluoroquinolones

“…Recently, however, several investigators [17][18][19] reported that Corynebacterium caused endophthalmitis postoperatively. In the current study, approximately 20% of Corynebacterium strains (6/29, 20.7%) were resistant to all fluoroquinolones studied.…”

Endophthalmitis Caused by Corynebacterium Species: Clinical Features, Antibiotic Susceptibility, and Treatment Outcomes

“…Corynebacterium has been previously described to be associated with endophthalmitis after YAG capsulotomy and has been demonstrated to stay sequestered within the capsular bag and even form a capsular hypopyon. 31, 32, 35 None of the patients in the current series required intraocular lens removal or capsulectomy, which is commonly required when treating endophthalmitis caused by Propionbacterium acnes , the most common cause of delayed-onset endophthalmitis. 46 Although persistently positive vitreous cultures in endophthalmitis caused by Corynebacterium species have been reported, there were no cases of persistently positive vitreous cultures in the current series.…”

Postoperative Endophthalmitis Caused by <b><i>Cutibacterium</i></b> (Formerly <b><i>Propionibacterium</i></b>) Acnes: Case Series and Review

“…It is thought that the capsulotomy liberates sequestered bacteria and mobilizes their spread into the vitreous cavity. Endophthalmitis following Nd:YAG capsulotomy is not unique to C. acnes , and has been described for other bacteria, including Staphylococcus epidermidis [ 28 ] and Corynebacterium species [ 29 ].…”