Introduction. Complications related to vascular access, alongside
cardiovascular diseases, constitute the primary cause of hospitalization
among patients undergoing hemodialysis. Thrombosis stands out as the most
prevalent cause of arteriovenous fistula dysfunction. The research aimed to
identify the risk factors contributing to thrombosis formation of the first
arteriovenous fistula. Material and Methods. The study spanned one year and
involved 40 patients who initiated hemodialysis through their first
arteriovenous fistula at the University Clinical Centre of Vojvodina. The
parameters analyzed included demographic, biochemical, and clinical factors,
as well as the therapy given. Results. Among the 40 patients, 67% were male.
The majority (57.5%) were aged over ? 60 years. Hypertension was the most
prevalent comorbidity, affecting 35% of patients. Arteriovenous fistula
thrombosis was diagnosed in 32% of patients. A logistical regression model
was employed to determine predictors of arteriovenous fistula thrombosis.
The analysis revealed that the patients with a body mass index greater than
> 25 kg/m2, had a 1.5 times higher risk of thrombosis formation. Similarly,
individuals with blood pressure exceeding > 140/90 mmHg had nearly a twofold
increased risk, while those in the 45-59 age group had a fourfold higher
risk. Patients who received anticoagulant therapy before arteriovenous
fistula formation had a 16 times lower risk of thrombosis, and nearly 33
times lower risk with the application of angiotensin-converting-enzyme
inhibitors/angiotensin II receptor blocker after arteriovenous fistula
formation. Conclusion. Significant predictors of thrombosis formation of the
first arteriovenous fistula among hemodialysis patients included body mass
index greater than > 25 kg/m2, blood pressure values exceeding > 140/90
mmHg, and age group of 45 - 69 years.