Late Prematurity in Twins: A Polish Multicenter Study

Abstract

The study aimed at investigating the impact of late prematurity (LPT) on neonatal outcome in twins and neonatal morbidity and mortality within LPT with regard to the completed weeks of gestation. The study was conducted in six tertiary obstetric departments from different provinces of Poland (Warsaw, Lublin, Poznan, Wroclaw, Bytom). It included 465 twin deliveries in the above centers in 2012. A comparative analysis of maternal factors, the course of pregnancy and delivery and neonatal outcome between LPT (34 + 0-36 + 6 weeks of gestation) and term groups (completed 37 weeks) was performed. The neonatal outcome included short-term morbidities. The analysis of neonatal complication rates according to completed gestational weeks was carried out. Out of 465 twin deliveries 213 (44.8%) were LPT and 156 (33.55%) were term. There were no neonatal deaths among LPT and term twins. One-third of LPT newborns suffered from respiratory disorders or required antibiotics, 40% had jaundice requiring phototherapy, and 30% were admitted to NICU. The analysis of neonatal morbidity with regard to each gestational week at delivery showed that most analyzed complications occurred less frequently with the advancing gestational age, especially respiratory disorders and NICU admissions. The only two factors with significant influence on neonatal morbidity rate were neonatal birth weight (OR = 0.43, 95% CI = 0.2-0.9, p = .02) and gestational age at delivery (OR = 0.62, 95% CI = 0.5-0.8, p < .01). LPT have a higher risk of neonatal morbidity than term twins. Gestational age and neonatal birth weight seem to play a crucial role in neonatal outcome in twins.

Female Sexual Function in Twin Pregnancy

“…It has been confirmed that the incidence of twin pregnancies has doubled over the course of the last fifty years, meaning that twins comprise almost 3% of all births in countries such as France or the USA [ 4 , 5 ]. According to a report in the Demographic Yearbook of Poland 2019, 2.5% of all births during the previous year originated from twin pregnancy [ 6 , 7 , 8 ].…”

A utilização da progesterona natural micronizada em gestações gemelares na prevenção do trabalho de parto prematuro

“…Apesar de todos os esforços e avanços da medicina perinatal, a taxa de mortalidade nas gestações múltiplas permanece mais alta do que a observada em gestações únicas 2 . Sendo assim, um desafio da prática obstétrica é prevenir a prematuridade e, para tal, várias estratégias estão sendo adotadas, como o uso profilático da progesterona exógena [4][5][6] .…”

Central and Eastern European Special Issue

“…Undeterred, today we are honored to be helping with the organization of the first Twins Congress in the region and, along with the abstracts of the conference, presenting a diverse set of articles on twin research from CEE and Hungary. First, Pári (2014) presents a historical and demographic overview of twin births in Hungary, followed by Kosinska-Kaczynska et al's (2014) Polish multicentric study on late prematurity in twins. Next is Hegedűs et al's (2014) sociological assessment of what advantages being a twin brings, followed by Molnár et al's (2014) case study of multiple valve disease found in triplets.…”