Lateral migration of a ferrofluid droplet in a plane Poiseuille flow under uniform magnetic fields

The influence of cell elastic modulus on inertial positions in Poiseuille microflows

“…It does, however, show an increase in the Ca of 8.5% in MCF-7 cell experiments with the addition of cytochalasin D and an increase of 50.7% in the Ca of experiments conducted with MDA-MB-231 cells after the addition of cytochalasin D. It can, therefore, be concluded that there is a relationship between the deformabilityinduced force and the elastic modulus of the suspended particle. Similar studies examining the trajectories of vesicles computationally (28,74), vesicles experimentally (29,75), and RBCs experimentally (26,76,77) have shown that a decrease in l p results in increased migration toward the channel center, a finding that agrees with the results presented in this study. Furthermore, previous measures of the viscosity of MCF-7 cells (70) result in l p -values in this experiment of $2.3, which are comparable values to some of those investigated in the above studies.…”

“…Indeed, it has been shown experimentally that the viscosity of a cell increases significantly with increased actin polymerization (70), implying that depolymerization results in decreased viscosity. This, in turn, reduces l p , which occurs with exposure to cytochalasin D. This pushes more deformable cells toward the channel center, which agrees with previous computational studies on droplets (28). For this reason, the size and shape of both treated and untreated cells in suspension were measured.…”

“…Taking into account the experimental parameters used in this study and the investigated values of E, Ca ranged from 1.4 Â 10 À8 -1.9 Â 10 À5 . This is quite low in comparison with those investigated previously (16,28,33,74); however, as previously mentioned, E cannot be assumed to be the absolute value of the elastic modulus of the cells in suspension, and so this value of Ca may not be accurate. It does, however, show an increase in the Ca of 8.5% in MCF-7 cell experiments with the addition of cytochalasin D and an increase of 50.7% in the Ca of experiments conducted with MDA-MB-231 cells after the addition of cytochalasin D. It can, therefore, be concluded that there is a relationship between the deformabilityinduced force and the elastic modulus of the suspended particle.…”

“…The E of the particle also heavily influences its migration speed, with more deformable particles reaching equilibrium positions quicker (13,28). Because previous studies have shown agreement of cell behavior in comparison to that of deformable droplets (29), it is anticipated that it will similarly affect the migration speeds of cells, with more pliable cells reaching their equilibrium positions faster than their stiffer counterparts.…”

Spreading Dynamics of an Impinging Ferrofluid Droplet on Hydrophilic Surfaces under Uniform Magnetic Fields

“…In addition to hydrodynamic forces, droplet manipulation can be achieved through the utilization of external forces, i.e., electric , or magnetic fields. − However, to attain magnetic control, either the continuous phase or droplet phase needs to be a ferrofluida fluid with magnetic properties, which due to its unique response to magnetic fields has gained immense popularity in numerous applications, including cancer treatment, sealing rotating shafts, and heat exchangers . Also, since ferrofluid offers greater flexibility in operations, it shows huge promise in a 3D metal printing process where the quality of printing, followed by shape distortion of metal, is defined by the overall spreading dynamics of the droplet during laser operation .…”