“…Currently, upconversion nanomaterials have been widely used in fields such as biological detection, biological imaging, biosensing, and immune analysis [7,8]. With the increasing severity of food safety issues, in order to improve the speed, sensitivity, and accuracy of detection, UCNPs have been applied to the detection of pesticide residues, mycotoxins, heavy metals, and other pollutants due to their unique advantages [9,10]. Qin et al [11] prepared two types of core-shell UCNPs, NaYF 4 : Yb, Er@NaYF 4 and Foods 2023, 12, 3445 2 of 14 NaYF 4 : Yb, Tm@NaYF 4 , and coupled them with two aptamers, OTA and ZEN, respectively, for the preparation of upconversion fluorescent probes, and established a magnetically controlled two-colour upconversion fluorescence method for the simultaneous determination of ochratoxin A (OTA) and zearalenone (ZEN) in maize and oat flour.…”