Layer-by-layer films of polysaccharides modified with polyethylene glycol and dextran

Shutava, Tatsiana G.; Livanovich, Kanstantsin S.; Sharamet, Anastasiya A.

doi:10.1016/j.colsurfb.2018.10.009

Cited by 21 publications

(25 citation statements)

References 69 publications

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“…Quartz sensors (Au-coated, AT-cut, nominal frequency 5 MHz) were used as templates for the assembly of LbL films. The deposition of LbL films and adsorption of FBS were performed according to the previously reported protocol with minimal modification [28].…”

Section: Quartz Crystal Microbalance (Qcm) Studymentioning

confidence: 99%

“…The mass of CH-SUB per cm 2 (m CH-SUB ) in the LbL films was evaluated using copolymers labeled with FITC. The protocol of copolymer labeling is described elsewhere [28]. The LbL films were formed by dipping glass slides in 1 mg/mL solutions of FITC-labeled CH-SUB and DS with intermediate washings in DI water.…”

Section: Determination Of Dry Polymer Adsorbed Mass and Water Content In The Lbl Filmsmentioning

confidence: 99%

“…DEX or PEG as side chains decrease adsorbed mass of fetal bovine serum proteins on LbL films made up from their graft copolymers with chitosan and dextran sulfate (DS) as polyanion [28]. The decrease in protein adsorption can be attributed to either specific structure of copolymer or the structure of LbL films.…”

Section: Introductionmentioning

confidence: 99%

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Layer-by-layer films of polysaccharides modified with poly(N-vinylpyrrolidone) and poly(vinyl alcohol)

Livanovich¹,

Sharamet²,

Shimko³

et al. 2021

Heliyon

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N-grafted copolymers of chitosan (460 kDa) with poly(N-vinylpyrrolidone) (2.4 kDa) or poly(vinyl alcohol) (2.0 kDa) as side chains were synthesized. Depending on the polymer-to-chitosan mass ratio the degree of amino group substitution with side chains in chitosan backbone was varied in the range of 0.01-0.33. Layer-by-layer films consisted of copolymers and dextran sulfate as polyanion were obtained. Thickness, hydrophilicity, and morphology of the films were investigated using QCM, UV-vis spectrophotometry, AFM, and contact angle measurements. The obtained films show enhanced protein-repellent properties in fetal bovine serum medium. The mass of adsorbed proteins on LbL films based on copolymer with a degree of substitution of 0.2 decreases by 50 % compared to unmodified chitosan. Protein-repellent properties of copolymer-based films are common for LbL films of grafted chitosan copolymers and depend on hydrophilic side chain density on the surface.

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Section: Quartz Crystal Microbalance (Qcm) Studymentioning

confidence: 99%

Section: Determination Of Dry Polymer Adsorbed Mass and Water Content In The Lbl Filmsmentioning

confidence: 99%

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Layer-by-layer films of polysaccharides modified with poly(N-vinylpyrrolidone) and poly(vinyl alcohol)

Livanovich¹,

Sharamet²,

Shimko³

et al. 2021

Heliyon

Self Cite

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“…Various other interactions have also been recently employed to construct LbL films, such as hydrogen bonding [4,5] and sugar-lectin binding [6,7]. The materials employed for this purpose have included synthetic polymers [8,9], polysaccharides [10][11][12], protein [13][14][15], and DNA [16,17]. Such layered multilayer films have found application in separation and purification [18,19], sensors [20,21], and drug delivery systems (DDSs) [22][23][24].…”

Section: Introductionmentioning

confidence: 99%

Decomposition of Glucose-Sensitive Layer-by-Layer Films Using Hemin, DNA, and Glucose Oxidase

et al. 2020

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Glucose-sensitive films were prepared through the layer-by-layer (LbL) deposition of hemin-modified poly(ethyleneimine) (H-PEI) solution and DNA solution (containing glucose oxidase (GOx)). H-PEI/DNA + GOx multilayer films were constructed using electrostatic interactions. The (H-PEI/DNA + GOx)5 film was then partially decomposed by hydrogen peroxide (H2O2). The mechanism for the decomposition of the LbL film was considered to involve more reactive oxygen species (ROS) that were formed by the reaction of hemin and H2O2, which then caused nonspecific DNA cleavage. In addition, GOx present in the LbL films reacts with glucose to generate hydrogen peroxide. Therefore, decomposition of the (H-PEI/DNA + GOx)5 film was observed when the thin film was immersed in a glucose solution. (H-PEI/DNA + GOx)5 films exposed to a glucose solution for periods of 24, 48 72, and 96 h indicated that the decomposition of the film increased with the time to 9.97%, 16.3%, 23.1%, and 30.5%, respectively. The rate of LbL film decomposition increased with the glucose concentration. At pH and ionic strengths close to physiological conditions, it was possible to slowly decompose the LbL film at low glucose concentrations of 1–10 mM.

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“…Such LbL films are prepared using various polymers for the development of thin film devices. Examples of the polymer materials used include synthetic polymers [ 10 , 11 ], polysaccharides [ 12 , 13 , 14 ], proteins [ 15 , 16 ], and DNA [ 17 , 18 , 19 ]. Thin films with various functions can be developed using polymers that are suitable for the intended application.…”

Section: Introductionmentioning

confidence: 99%

Adsorption and Release of Rose Bengal on Layer-by-Layer Films of Poly(Vinyl Alcohol) and Poly(Amidoamine) Dendrimers Bearing 4-Carboxyphenylboronic Acid

et al. 2020

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Phenylboronic acid-bearing polyamidoamine dendrimer (PBA-PAMAM)/poly(vinyl alcohol) (PVA) multilayer films were prepared through the layer-by-layer (LbL) deposition of PBA-PAMAM solution and PVA solution. PBA-PAMAM/PVA films were constructed successfully through the formation of boronate ester bonds between the boronic acid moiety in PBA and 1,3-diol units in PVA. When the (PBA-PAMAM/PVA)5 films were immersed in rose bengal (RB) solution, RB was adsorbed onto the LbL films. The amount of RB adsorbed was higher in the LbL films immersed in acidic solution than in basic solution. The release of RB from the LbL films was also promoted in the basic solution, while it was suppressed in the acidic solution. The boronic acid ester is oxidized to phenol by hydrogen peroxide (H2O2) and the carbon-boron bond is cleaved, so that the (PBA-PAMAM/PVA)5 films can be decomposed by immersion in H2O2 solution. Therefore, when RB-adsorbed (PBA-PAMAM/PVA)5 films were immersed in H2O2 solution, the release of RB was moderately promoted when the solution was weakly acidic.

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Layer-by-layer films of polysaccharides modified with polyethylene glycol and dextran

Cited by 21 publications

References 69 publications

Layer-by-layer films of polysaccharides modified with poly(N-vinylpyrrolidone) and poly(vinyl alcohol)

Layer-by-layer films of polysaccharides modified with poly(N-vinylpyrrolidone) and poly(vinyl alcohol)

Decomposition of Glucose-Sensitive Layer-by-Layer Films Using Hemin, DNA, and Glucose Oxidase

Adsorption and Release of Rose Bengal on Layer-by-Layer Films of Poly(Vinyl Alcohol) and Poly(Amidoamine) Dendrimers Bearing 4-Carboxyphenylboronic Acid

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